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M. leprae Br4923 MLBr_00142 (-)

annotation: hypothetical protein MLBr_00142
coordinates: 204390 - 204638
length: 82

LIAAIPPEPTSTYLVLLQIGMYGMMLLTGVPVLIQAVLPELLRRDFDHDLVHQPETMNLFVELFVPYLLA
TGYTGSLSPTTR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00142--100% (82)hypothetical protein MLBr_00142

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_1403-2e-1659.70% (67) peptidase M1, membrane alanine aminopeptidase
M. tuberculosis H37Rv-----
M. abscessus ATCC 19977MAB_0509c-3e-1347.06% (68) peptidase M1, membrane alanine aminopeptidase
M. marinum MMMAR_5284pepN_11e-1858.82% (68) aminopeptidase N PepN_1
M. avium 104-----
M. smegmatis MC2 155MSMEG_6138-3e-1761.19% (67) metallopeptidase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4357pepN_18e-1958.82% (68) aminopeptidase N PepN_1
M. vanbaalenii PYR-1Mvan_5387-6e-1659.70% (67) peptidase M1, membrane alanine aminopeptidase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_0509c|M.abscessus_ATCC_199      MTKPGKKAAKRLPPRPPVIDPYLPQNGNYGYRVSRYELDLEYKVAINRLT
MSMEG_6138|M.smegmatis_MC2_155      MTRS-KKVAKKAG-HPPVIDPYLPGNGNFGYRVSRYELDLEYKVASNRLT
Mflv_1403|M.gilvum_PYR-GCK          -------MSKKNS--SPVIDPYLPEAGNFGYRVSRYELDLEYKTTINRLS
Mvan_5387|M.vanbaalenii_PYR-1       MTAR-KRAAKKSS--PPVIDPYLPGAGNFGYRVSRYELELEYKVTINRLS
MMAR_5284|M.marinum_M               MKASAKMPKKAIK----IIDPYLPQNGNFGYRVSRYELDLEYKVAINRLS
MUL_4357|M.ulcerans_Agy99           MKASAKMPKKAIK----IIDPYLPQNGNFGYRVSRYELDLEYKVAINRLS
MLBr_00142|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_0509c|M.abscessus_ATCC_199      GTANITAVTLATIKEFTLDLADTLGVAKVTVNGRRPTHFGHRAGKITIKL
MSMEG_6138|M.smegmatis_MC2_155      GTATITAVTLAALRTFTLDLSDNLSVGKVSVNGRRPAQFRCSGAKLHITL
Mflv_1403|M.gilvum_PYR-GCK          GSAAITAVTLAEIKTFTLDLADALSVSKVSVNGKRPAHYRTAAGKLHITL
Mvan_5387|M.vanbaalenii_PYR-1       GAATITAVTLAELKTFTLDLSGALSVSKVTVNGRRPAHYRTSADKLHITL
MMAR_5284|M.marinum_M               GTATITAVTLTELQEFTLDLSDALSVSKVLVNGKRVARFASRNGKLRIGL
MUL_4357|M.ulcerans_Agy99           GTATITAVTLTELQEFTLDLSDALSVLKVLVNGKRVAHFASRNGKLRIGL
MLBr_00142|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_0509c|M.abscessus_ATCC_199      ASAIPAGAAMTIVIRYGGSPRPINSMWGDVGFEELSNGVLVAGQPNGAAS
MSMEG_6138|M.smegmatis_MC2_155      PAALPAGSAMTVVIRYSGNPRPIDTLWGDVGFEELTNGALVAGQPNGAAS
Mflv_1403|M.gilvum_PYR-GCK          AERLPAGAAMTVGIRYSGNPRPNRTPWGDVGFEELTEGVLVAGQPNGASS
Mvan_5387|M.vanbaalenii_PYR-1       SERLPAGAAMTIAVRYGGTPRPIRSLWGEVGFEELTDGVLVAGQPNGASS
MMAR_5284|M.marinum_M               TSKLATGVAFSVLVRYSGAPRPLQTLWGEVGFEELTEGALVAGQPNGAAS
MUL_4357|M.ulcerans_Agy99           TSKLATGVAFSVLVRYSGAPRPLQTLWGEVGFEELTEGALVAGQPNGAAS
MLBr_00142|M.leprae_Br4923          ---------------------------------------MIAAIP-----
                                                                           ::*. *     

MAB_0509c|M.abscessus_ATCC_199      WFPCDDHPSSKASYRFVITSDSPYCVISNGELISRRVRAAHTTWTYEQPE
MSMEG_6138|M.smegmatis_MC2_155      WFPCDDHPSAKASYRIQISTDSPYHAVANGELLSRKVRAGHTVWTYELAE
Mflv_1403|M.gilvum_PYR-GCK          WFPCDDHPAAKASFRVQIATESPYFALANGKLLSRRPRAGMTTWVYEQSE
Mvan_5387|M.vanbaalenii_PYR-1       WFPCDDHPSAKASFRVQIATESAYFALANGKLLTRRARAGMTTWIYEQAE
MMAR_5284|M.marinum_M               WFPCNDHPSAKAAFRIQISTESSYRAIANGKLVGQRVRASQTVWTYEQPE
MUL_4357|M.ulcerans_Agy99           WFPCNDHPSAKAAFRIQISTESSYRAIANGKLVGQRVRASPTVWTYEQPE
MLBr_00142|M.leprae_Br4923          ------------------------------------------------PE
                                                                                    .*

MAB_0509c|M.abscessus_ATCC_199      PMAPYLATLQIGDYQLVKLAKNPISMNAALPSRLRDRFEHDFGRQPQMMK
MSMEG_6138|M.smegmatis_MC2_155      PTSPYLVTLQIGMYESHRMTKTPVPMHAVLPPRLRSAFDHDFERQPQMMK
Mflv_1403|M.gilvum_PYR-GCK          PTSTYLITLQIGVYNRHRLSKNGVEIFAVLPDRLRREFAHDFGRQPQMMK
Mvan_5387|M.vanbaalenii_PYR-1       PTSTYLITLQIGMYERHRMAKNGVEIFAVLPRRLRDDFDHDFGRQPQMMK
MMAR_5284|M.marinum_M               PTSTYLITLQVGVYVMARMSRSPVPIRAALPERLRSEFDHDFAGQPAMMQ
MUL_4357|M.ulcerans_Agy99           PTSTYLITLQVGVYVMARMSRSPVPIRAALPERLRSEFDHDFAGQPAMMQ
MLBr_00142|M.leprae_Br4923          PTSTYLVLLQIGMYGMMLLTGVPVLIQAVLPELLRRDFDHDLVHQPETMN
                                    * :.**  **:* *    ::   : : *.**  **  * **:  **  *:

MAB_0509c|M.abscessus_ATCC_199      LFIKQFGPYPFAAGYTVVVTDDDLDIPLEAQGISVFGANHCDGSRHSERL
MSMEG_6138|M.smegmatis_MC2_155      LFVKLFGPYPLSTGYTVVVTDDDLEIPLEAQGISIFGANHCDGSRGSERL
Mflv_1403|M.gilvum_PYR-GCK          LFTKLFGPYPLATGYTVVVTDDDLEIPLEAQGISIFGANHCDGSRKAERL
Mvan_5387|M.vanbaalenii_PYR-1       LFTKLFGPYPLANGYTVVVTDDDLEIPLEAQGISIFGANHCDGRRGEERL
MMAR_5284|M.marinum_M               LFIDLFGPYPLANGYTVVVTDDALEIPLEAQGISIFGANHCDGTRSSERL
MUL_4357|M.ulcerans_Agy99           LFIDLFGPYPLANGYTVVVTDDALEIPLEAQGISIFGANHCDGTRSSERL
MLBr_00142|M.leprae_Br4923          LFVELFVPYLLATGYT--------------------------GS------
                                    ** . * ** :: ***                          *       

MAB_0509c|M.abscessus_ATCC_199      VAHELAHQWFGNSVTARRWRDIWLHEGFACYAEWLWSEESGGPTADARAR
MSMEG_6138|M.smegmatis_MC2_155      IAHELAHQWFGNSVTARRWRDIWLHEGFACYAEWLWSENSGGRGAAEWAQ
Mflv_1403|M.gilvum_PYR-GCK          IAHELAHQWFGNSVTVQRWRHIWLHEGFACYAEWLWSEHCGERTAQQWAQ
Mvan_5387|M.vanbaalenii_PYR-1       IAHELAHQWFGNSVTVQRWRHIWLHEGFACYAEWLWSEHCGERTVDQWAR
MMAR_5284|M.marinum_M               IAHELAHQWFGNSVTARRWCDIWLHEGFACYAEWLWSEHSGGPSADELAR
MUL_4357|M.ulcerans_Agy99           IAHELAHQWFGNSVTARRWCDIWLHEGFACYAEWLWSEHSGGPSADELAR
MLBr_00142|M.leprae_Br4923          -----------LSPTTR---------------------------------
                                                * *.:                                 

MAB_0509c|M.abscessus_ATCC_199      HYHQKLKDLPQDLILADPGPQLMFDDRVYKRGALTLHALRLRLGDTKFFA
MSMEG_6138|M.smegmatis_MC2_155      HYYDKLRHSPQDLLLADPGPRDMFDDRVYKRGALTLHVLRERIGDKNFFA
Mflv_1403|M.gilvum_PYR-GCK          HYHHRLKHSPHDLVLADPGPRDMFDDRVYKRGALTLHVLRQRIGDANFFA
Mvan_5387|M.vanbaalenii_PYR-1       HYHERLKNSPHNLVLADPGPRDMFDDRVYKRGALTLHALRNHIGDTEFFA
MMAR_5284|M.marinum_M               YHHQELRGKPQDLLLTDPGPQLMFDDRVYKRGALALHSLRGRLGDAKFFA
MUL_4357|M.ulcerans_Agy99           YHHQELRGKPQDLLLTDPGPQLMFDDRVYKRGALALHSLRGRLGDAKFFA
MLBr_00142|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_0509c|M.abscessus_ATCC_199      LLQDWTTRYRHSTVITDDFTGLAAGYSDESLRPLWTAWLYEKQLPPLDRK
MSMEG_6138|M.smegmatis_MC2_155      LLQDWTTRHRHGTAFTDDFTGLAAGYTSESLQPLWQAWLYSEALPPL---
Mflv_1403|M.gilvum_PYR-GCK          LLKDWTTRYRHSSVVTDDFLGLASQYSDESLRSLWAAWLYSTEVPALDAG
Mvan_5387|M.vanbaalenii_PYR-1       LLKDWTNRYRHSSVVTDDFVGLAARYAHDSLRPLWAAWLYSPEVPELDAG
MMAR_5284|M.marinum_M               LLRDWTTRYRHGTVITDDFTGLAANYATESLRDLWDTWLYSTAVP-----
MUL_4357|M.ulcerans_Agy99           LLRDWTTRYRHGTVITDDFTGLAANYATESLRDLWDTWLYSTAVP-----
MLBr_00142|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_0509c|M.abscessus_ATCC_199      -
MSMEG_6138|M.smegmatis_MC2_155      -
Mflv_1403|M.gilvum_PYR-GCK          S
Mvan_5387|M.vanbaalenii_PYR-1       S
MMAR_5284|M.marinum_M               -
MUL_4357|M.ulcerans_Agy99           -
MLBr_00142|M.leprae_Br4923          -