For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_4476 (-)

annotation: creatininase subfamily protein
coordinates: 4604254 - 4604985
length: 243

NSSYHHRVSVLGELGTVTSSQLSGTAVSLLVPLGSTEQHGPHLPLDTDTRIASAVAGRAAPRLGDGWLVA
PAIAYGASGEHQSFAGTVSIGTEALTLLLIEYGRSAAGWAQRVVFVNGHGGNVAALGRAVGTLRAEGRDA
GWCPCVAAGGDAHAGHTETSVLLHISPAEVRTGQWQAGNRAPLPELLGSMRRGGVAAVSPVGVLGDPTTA
TAAEGERILSEMVNECVRRVARWRPGPDGMLA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4476--100% (243)creatininase subfamily protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0714-1e-10775.60% (250) hypothetical protein Mb0714
M. gilvum PYR-GCKMflv_5058-6e-8364.00% (250) creatininase
M. tuberculosis H37RvRv0695-1e-10775.60% (250) hypothetical protein Rv0695
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3832c-5e-8162.35% (247) hypothetical protein MAB_3832c
M. marinum MMMAR_1023-1e-10274.30% (249) creatinine amidohydrolase
M. smegmatis MC2 155MSMEG_1425-3e-8067.28% (217) creatininase subfamily protein
M. thermoresistible (build 8)TH_1902-3e-6964.85% (202) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0775-1e-10173.90% (249) creatinine amidohydrolase
M. vanbaalenii PYR-1Mvan_1298-9e-8867.07% (246) creatininase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0714|M.bovis_AF2122/97            MNSSYHRRVPVVGELGSATSSQLPSTS----PSIVIPLGSTEQHGPHLPL
Rv0695|M.tuberculosis_H37Rv         MNSSYHRRVPVVGELGSATSSQLPSTS----PSIVIPLGSTEQHGPHLPL
MAV_4476|M.avium_104                MNSSYHHRVSVLGELGTVTSSQLSGTA----VSLLVPLGSTEQHGPHLPL
MMAR_1023|M.marinum_M               MNSSYHRRVPVLGELGTSTSSQLPSTS----PSILIPLGSTEQHGPHLPL
MUL_0775|M.ulcerans_Agy99           MNSSYHRRVPVLGELGTSTSSQLPSTW----PSILIPLGSTEQHGPHLPL
Mflv_5058|M.gilvum_PYR-GCK          MNSAYHRRVVFPRELGNSTSRQLHDAHAIHMPTLVVPVGSTEQHGPHLPL
Mvan_1298|M.vanbaalenii_PYR-1       MNSAYHRRVVFPRELGNSTSRQLQHES----PTLVVPVGSTEQHGPHLPL
MSMEG_1425|M.smegmatis_MC2_155      -----------------------------MVPMVLVPVGSTEQHGPHLPL
TH_1902|M.thermoresistible__bu      -------------------------------------------------L
MAB_3832c|M.abscessus_ATCC_199      MNSAYHRRVAVPTVLSTAISPELSDEA----ITLFTPLGSTEQHGPHLPL
                                                                                     *

Mb0714|M.bovis_AF2122/97            DTDTRIATAVARTVTARLHAEDLPIAQEEWLMAPAIAYGASGEHQRFAGT
Rv0695|M.tuberculosis_H37Rv         DTDTRIATAVARTVTARLHAEDLPIAQEEWLMAPAIAYGASGEHQRFAGT
MAV_4476|M.avium_104                DTDTRIASAVAGRAAPRLG--------DGWLVAPAIAYGASGEHQSFAGT
MMAR_1023|M.marinum_M               DTDTRIATAVGRAVATRMHG-RLTQCQPGWLLAPPIAYGASGEHQSFAGT
MUL_0775|M.ulcerans_Agy99           DTDTRIATAVGRAVATRMHG-RLTQCQPGWLLAPPIAYGASGEHQSFAGT
Mflv_5058|M.gilvum_PYR-GCK          DTDTRIATAVADAVVTRLRARD----ETHWVMAPAIAYGASGEHEGFPGT
Mvan_1298|M.vanbaalenii_PYR-1       DTDTRIASAVADALVTRLRAGG----GPDWLIAPAIGYGASGEHEGFAGT
MSMEG_1425|M.smegmatis_MC2_155      DTDTRIAAAVAGTVVEQFGAPA----DRDAVVAPPVAYGASGEHEGFPGT
TH_1902|M.thermoresistible__bu      DTDTRIAGAVARAVIERLTAADG---DTRWLLAPPICYGASGEHEGFPGT
MAB_3832c|M.abscessus_ATCC_199      DTDTRIAGAVATGAAAELAADGG---DGRTALAPAIAYGASGEHQSFAGT
                                    ******* **.     .:             :**.: *******: *.**

Mb0714|M.bovis_AF2122/97            ISIGTEALTMLLVEYGRSAACWARRLVFVNGHGGNVGALTRAVGLLRAEG
Rv0695|M.tuberculosis_H37Rv         ISIGTEALTMLLVEYGRSAACWARRLVFVNGHGGNVGALTRAVGLLRAEG
MAV_4476|M.avium_104                VSIGTEALTLLLIEYGRSAAGWAQRVVFVNGHGGNVAALGRAVGTLRAEG
MMAR_1023|M.marinum_M               ISIGTEALRVLLLEYGRSAACWADRLVFVNGHGGNVEALRGAVRQLRAEG
MUL_0775|M.ulcerans_Agy99           ISIGAEALRVLLLEYGRSAACWADRLVFVNGHGGNVEALRGAVRQLRAEG
Mflv_5058|M.gilvum_PYR-GCK          ISIGTPALAELLVEFVRSACRWTPRVAFVNGHGGNVDALRRAVTQLRHEG
Mvan_1298|M.vanbaalenii_PYR-1       VSIGTPVLAELLTEFARSACRWAPRVVFVNGHGGNVEALRRAVTLLRHEG
MSMEG_1425|M.smegmatis_MC2_155      VSIGTAALELLLVEYGRSASKWTSRIVFVNGHGGNVEALAAAVALLRYEG
TH_1902|M.thermoresistible__bu      VSVGTPALRLWLVEYGRSAANWASRLVFLNGHGGNVEALAAATALLRYEN
MAB_3832c|M.abscessus_ATCC_199      ISIGTEVLGRLLVEYARSAIQWCRRIVIVNGHGGNIQGLVSAVRLLRSEG
                                    :*:*: .*   * *: ***  *  *:.::******: .*  *.  ** *.

Mb0714|M.bovis_AF2122/97            RDAGWCPCTCPGGDPHAGHTETSVLLHLSPADVRTERWRAGNRAPLPVLL
Rv0695|M.tuberculosis_H37Rv         RDAGWCPCTCPGGDPHAGHTETSVLLHLSPADVRTERWRAGNRAPLPVLL
MAV_4476|M.avium_104                RDAGWCPCVAAGGDAHAGHTETSVLLHISPAEVRTGQWQAGNRAPLPELL
MMAR_1023|M.marinum_M               RDAGWSACGSAGGDAHAGHTETSVLLHISPEVVLTDRLSAGNAAPLAELL
MUL_0775|M.ulcerans_Agy99           RDAGWSACGSAGGDAHAGHTETSVLLHISPEVVLTDRLSAGNAAPLAELL
Mflv_5058|M.gilvum_PYR-GCK          RDAAWSPCVAGNADAHAGHTETSVLLHLSPDAVRQEERVPGNRAPLAELM
Mvan_1298|M.vanbaalenii_PYR-1       RDAVWCPCTSSNADAHAGHTETSVLLHISPAAVRQDERVPGNRAPLSELM
MSMEG_1425|M.smegmatis_MC2_155      RDAGWVPCSVPDADAHAGHTETSVLLHISPDDVLTDELVCGNTAPLAELM
TH_1902|M.thermoresistible__bu      RDAAWLSCLAAGGDAHAGHTETSVLLHLSPEVVSTEHVLPGNSAPLAELM
MAB_3832c|M.abscessus_ATCC_199      RDVAWWACAVEGGDAHAGHVETSLLLHISPDVVRREEVLAGNVAPLHELM
                                    **. * .*   ..*.****.***:***:**  *   .   ** ***  *:

Mb0714|M.bovis_AF2122/97            PSMRRGGVAAVSETGVLGDPTTATAAEGRRIFAAMVDDCVRRVARWMPQP
Rv0695|M.tuberculosis_H37Rv         PSMRRGGVAAVSETGVLGDPTTATAAEGRRIFAAMVDDCVRRVARWMPQP
MAV_4476|M.avium_104                GSMRRGGVAAVSPVGVLGDPTTATAAEGERILSEMVNECVRRVARWRPGP
MMAR_1023|M.marinum_M               PSLRRGGVAAVSPIGVLGDPTTATAVEGRRIFAEMVDDCVSRIARWTPGP
MUL_0775|M.ulcerans_Agy99           PSLRRGGVAAVSPIGVLGDPTTATAVEGRRIFAEMVDDCVSRIARWTPGP
Mflv_5058|M.gilvum_PYR-GCK          PQMLRGGVAAVSSLGVLGDPTTATADEGRRIFAEMVDACAARVVRWEPDR
Mvan_1298|M.vanbaalenii_PYR-1       PEMLRGGVAAVSSLGILGDPTTATADEGRRIFAEMVDACAVRVIRWAPDR
MSMEG_1425|M.smegmatis_MC2_155      PRMRSGGVAAVSELGILGDPTTATAAEGERIFAEMVNGCADRIKRWQPDR
TH_1902|M.thermoresistible__bu      PQLRAGGVAAVSEVGILGDPTTATAAAGARIFADMVDDCVERITRWTANR
MAB_3832c|M.abscessus_ATCC_199      APMRAGGVAAVSAIGVLGDPTTASSQDGARMLETMTRQCADAVRRWTPDA
                                      :  *******  *:*******::  * *::  *.  *.  : ** .  

Mb0714|M.bovis_AF2122/97            DGMLT
Rv0695|M.tuberculosis_H37Rv         DGMLT
MAV_4476|M.avium_104                DGMLA
MMAR_1023|M.marinum_M               DGMLT
MUL_0775|M.ulcerans_Agy99           DGMLT
Mflv_5058|M.gilvum_PYR-GCK          GGMLT
Mvan_1298|M.vanbaalenii_PYR-1       GGMLT
MSMEG_1425|M.smegmatis_MC2_155      NGLLT
TH_1902|M.thermoresistible__bu      DGMLT
MAB_3832c|M.abscessus_ATCC_199      DGRLV
                                    .* *.