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VAAATIAVVVAATAALIWWTSDARATVSRPAAVPAPNPSPARQVPASLKQLWTAASPATTEPVVVGGVVA TGAGRRIDGRDPATGQSRWSYARDTDLCGLSWLYRYAVGVYRDDRGCGQVSTLDGSTGRRGPARSGYADP RVRLSSDGMTVLSVGDTRLELWRSDMVRMLTYGETDARVKPSARGLHSGCRLISAAASSSAVSVLESCAN QADLRLVLLRPGKDDDEPQQHIVAEPGIAPDSGARVLAVREATTAVYLPAPRPRVDVIDETGTTVSSTPL PRPPSPSAAVSHAGSVMTWWTGDSLMVFDVNTLALRYTIAAGDKTAPLGPGAMMAGRLLVPVTGAIGVYD PISGASERYIPVDRATGGAPPGAAVVPAVSGSRVFEQRGDTVVALG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4160 | - | - | 100% (396) | hypothetical protein MAV_4160 |
| M. avium 104 | MAV_2055 | - | 5e-05 | 26.20% (187) | cysteine desulphurases, SufS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3238 | - | 1e-173 | 76.13% (398) | hypothetical protein Mb3238 |
| M. gilvum PYR-GCK | Mflv_4677 | - | 1e-125 | 57.96% (383) | hypothetical protein Mflv_4677 |
| M. tuberculosis H37Rv | Rv3212 | - | 1e-173 | 76.13% (398) | hypothetical protein Rv3212 |
| M. leprae Br4923 | MLBr_00810 | - | 1e-169 | 73.43% (399) | hypothetical protein MLBr_00810 |
| M. abscessus ATCC 19977 | MAB_3532 | - | 1e-91 | 46.62% (399) | hypothetical protein MAB_3532 |
| M. marinum M | MMAR_1345 | - | 1e-173 | 74.49% (396) | hypothetical protein MMAR_1345 |
| M. smegmatis MC2 155 | MSMEG_1929 | - | 1e-132 | 58.59% (396) | hypothetical protein MSMEG_1929 |
| M. thermoresistible (build 8) | TH_0649 | - | 6e-86 | 58.48% (277) | CONSERVED HYPOTHETICAL ALANINE VALINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_2534 | - | 1e-172 | 73.99% (396) | hypothetical protein MUL_2534 |
| M. vanbaalenii PYR-1 | Mvan_1790 | - | 1e-134 | 58.59% (396) | hypothetical protein Mvan_1790 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4677|M.gilvum_PYR-GCK ------------------------MAAVVWWTSDARATRSTPAAEPLPSL
Mvan_1790|M.vanbaalenii_PYR-1 MVKPERRTRADLVAAAAIAGVVALVAAVVWWTSDARATESRPAAEPVPSL
MSMEG_1929|M.smegmatis_MC2_155 MVKPERRTRGDIVAAAVIVVVVAVAAGLIWWTSDARATLSRPAAAPVPYL
TH_0649|M.thermoresistible__bu --------------------------------------------------
Mb3238|M.bovis_AF2122/97 MVKPERRTKTDIAAAATIAVVVAVAASLIWWTSDARATISRPAAVAVPTP
Rv3212|M.tuberculosis_H37Rv MVKPERRTKTDIAAAATIAVVVAVAASLIWWTSDARATISRPAAVAVPTP
MMAR_1345|M.marinum_M MVKPERRTRGDILAAAAIVVVIALVTLLIWWTSDARATVSRPAAAPAPNP
MUL_2534|M.ulcerans_Agy99 MVKPERRTRGDILAAAAIVVVIALVTLLIWWTSDARATVSRPAAAPAPNP
MLBr_00810|M.leprae_Br4923 MVRPERRTKADTIAAMTITVVMAAMVSLIWWTSDAQATHSRPATIPAPNP
MAV_4160|M.avium_104 ------------MAAATIAVVVAATAALIWWTSDARATVSRPAAVPAPNP
MAB_3532|M.abscessus_ATCC_1997 MIAPERRTRADIIAAAVIAVVVAVTGTTIWWTSDARATVSRPAAGDIKRP
Mflv_4677|M.gilvum_PYR-GCK KPAVAVPDSLTQLWAARSGETTRPLVVGGAVVTGDGQAMQGREPATGDVV
Mvan_1790|M.vanbaalenii_PYR-1 KPAAAVPDSLEQRWTTGSAKTTLPVVVGGAVVTGDGQAMEGRDPATGATL
MSMEG_1929|M.smegmatis_MC2_155 TPAAEVPAGLHEMWTAPSPKTTAPVVAGGAVVTGDGRTVDGRDPISGAVL
TH_0649|M.thermoresistible__bu --------------------------------------------------
Mb3238|M.bovis_AF2122/97 APAREVPTSLKQLWTAASPATRVPVVVGGTVATGDGRQVDGRDPATGESL
Rv3212|M.tuberculosis_H37Rv APAREVPTSLKQLWTAASPATRVPVVVGGTVATGDGRQVDGRDPATGESL
MMAR_1345|M.marinum_M SPAREVPGTLKQLWTANSPATRVPVVAGGTVATGTGRLVEGRNPTTGETL
MUL_2534|M.ulcerans_Agy99 SPAREVPGTLKQLWTANSPATRVPMVAGGTVATGAGRLVEGRNPTTGETL
MLBr_00810|M.leprae_Br4923 TPAREVPTAFNQLWAAASPATTAPVVVGGAVITGDGHQIDGRNPVTGESR
MAV_4160|M.avium_104 SPARQVPASLKQLWTAASPATTEPVVVGGVVATGAGRRIDGRDPATGQSR
MAB_3532|M.abscessus_ATCC_1997 MSATRVPDSVRELWSTASAATKGPVIASGAVVSADGHDVVAHDPATGAQL
Mflv_4677|M.gilvum_PYR-GCK WSYAR-DLDLCGVTWVYNYAVAVYPDARGCGQVSTVDAKTGRRGPARTSY
Mvan_1790|M.vanbaalenii_PYR-1 WRYAR-DLELCGVTWVYSYAVAVYPDVRGCGQVSTVDAKTGLRGPSRTSY
MSMEG_1929|M.smegmatis_MC2_155 WTYAR-DADLCGVTSVYSYAVAVYPDVRGCGQVSTIDGRTGMRGPARTAF
TH_0649|M.thermoresistible__bu --------------------------------VSTIDGDTGRRGPARSGY
Mb3238|M.bovis_AF2122/97 WSYAR-DTDLCGVTWVYHYAVAVYRYDRGCGQVSTIDGSTGRRGAARSGY
Rv3212|M.tuberculosis_H37Rv WSYAR-DTDLCGVTWVYHYAVAVYRYDRGCGQVSTIDGSTGRRGAARSGY
MMAR_1345|M.marinum_M WSYSR-DTDLCGVSWVYRYAVAVYRDDRGCGQVSTIDGSTGRRGPARSSY
MUL_2534|M.ulcerans_Agy99 WSYSR-DTDLCGVSWVYRYAVAVYRDDRGCGQVSTIDGSTGRRGPARSSY
MLBr_00810|M.leprae_Br4923 WSYAR-DSDLCGVSWVYHYAVAVYRDDRGCGQVSTIDGSTGRREAARSSY
MAV_4160|M.avium_104 WSYAR-DTDLCGLSWLYRYAVGVYRDDRGCGQVSTLDGSTGRRGPARSGY
MAB_3532|M.abscessus_ATCC_1997 WSYARRNLDLCGAIGFIDDAVAVYRDARGCGQVTMIDGQTGRRGALRSSA
*: :*. ** * . *:.
Mflv_4677|M.gilvum_PYR-GCK ADRHVTLSGDGSTVLSQGETRLEMWRSDMVRMLSYGALDAPIKPGVP-AT
Mvan_1790|M.vanbaalenii_PYR-1 ADREVTLSADGTTVLSAGATRLEMWRSDMVRMLSYGALDAPIKPGVP-AS
MSMEG_1929|M.smegmatis_MC2_155 ADPEVKLSTDGVTVLSGGDSRLELWRSDMVRMLSYGALDARIKPDVP-AS
TH_0649|M.thermoresistible__bu ADREVTLSSDGATVLSAGDSRLELWRSDMVRMLSYGYLDAPIKPDVP-TT
Mb3238|M.bovis_AF2122/97 ADPRVRLFSDGTTVLSAGDTRLELWRSDMVRMLAYGEIDARVKPSNRGLQ
Rv3212|M.tuberculosis_H37Rv ADPRVRLFSDGTTVLSAGDTRLELWRSDMVRMLAYGEIDARVKPSNRGLQ
MMAR_1345|M.marinum_M ADPKVRLSSDGTTVLSAGSTRLELWRSDMVRMLSYGETDARVKPANRGLH
MUL_2534|M.ulcerans_Agy99 ADPKVRLSSDGTTVLSAGSTRLELWRSDMVRMLSYGETDARVKAANRGLH
MLBr_00810|M.leprae_Br4923 ADPHVRLSSDGTAVLSAGDTRLELWRSDMVRMLAYGEIDARVKPPARGLH
MAV_4160|M.avium_104 ADPRVRLSSDGMTVLSVGDTRLELWRSDMVRMLTYGETDARVKPSARGLH
MAB_3532|M.abscessus_ATCC_1997 NDSKVSLSTDGTYVLALGSTRLELWRSDMVRTLEYGRVVAPLNANSQ-PR
* .* * ** **: * :***:******* * ** * ::.
Mflv_4677|M.gilvum_PYR-GCK PLCRFVSAGASSDSVSVLEACESQ-DLRLTLLRPS-DEEDSPEAKYVQ-Q
Mvan_1790|M.vanbaalenii_PYR-1 PLCRFVSAGASASSVSVLESCESQADLRLTLLRPS-DEEDTPELKYVQ-Q
MSMEG_1929|M.smegmatis_MC2_155 PVCRQLSAAASSSAVSVIESCPKTDEVRLTLLRPA-DEEDTPDLRYVE-L
TH_0649|M.thermoresistible__bu PLCRLESAAASSAMVSVLEACPKQPDLRLTLLRVT-DEEDVPEAKYVA-L
Mb3238|M.bovis_AF2122/97 SGCTLESAAASSAAVSVLEACTNQADLRLVLLRPG-KEDDEPIQRIVP-E
Rv3212|M.tuberculosis_H37Rv SGCTLESAAASSAAVSVLEACTNQADLRLVLLRPG-KEDDEPIQRIVP-E
MMAR_1345|M.marinum_M SGCTLESAAASSSAVSVLEACQDQADLRLVLLRPG-KEEDEPEQRIVP-E
MUL_2534|M.ulcerans_Agy99 SGCTLESAAASSSAVSVLEACQDQADLRLVLLRPG-KEEDEPEQRIVP-E
MLBr_00810|M.leprae_Br4923 SGCTLESTAASSSAVAVLEACANQDDLQLVLLRPG-KEDDEPQQHLVA-E
MAV_4160|M.avium_104 SGCRLISAAASSSAVSVLESCANQADLRLVLLRPG-KDDDEPQQHIVA-E
MAB_3532|M.abscessus_ATCC_1997 VDCTLKSGAVGASVLAVLETCPQDPTLRLTLQKPTPKDNDKPEELYSAVL
* * ...: ::*:*:* . ::*.* : .::* *
Mflv_4677|M.gilvum_PYR-GCK TGVADGTGARVVAVSDTYTALYVPT---PKPRLDLIDDTGATVDTTIVDG
Mvan_1790|M.vanbaalenii_PYR-1 KGVADGSGARVVAVTDSATALYVPT---PKPRIDIIDDTGAVIDSTVVPA
MSMEG_1929|M.smegmatis_MC2_155 PGVTDESGAQVIAVSDTTTAIYVPT---PEPKVDVIDETGATVASTILPK
TH_0649|M.thermoresistible__bu PGVAPDSGARVIAVSSRTTAVYVPT---PTPVVNIVDETGTTVASTLVER
Mb3238|M.bovis_AF2122/97 PGARPGSGARVLVVSQNNTAVYLPARSGAQPRVDVIDETGATVSSTLLAK
Rv3212|M.tuberculosis_H37Rv PGVRPGSGARVLVVSQNNTAVYLPARSGAQPRVDVIDETGATVSSTLLAK
MMAR_1345|M.marinum_M PGIRAGSGARVLIVSQNNTAVYLPS---PQPHVEVIDETGTTTASTLLPK
MUL_2534|M.ulcerans_Agy99 PGIRAGSGARVLIVSQNNTAVYLPS---PQPHVEVIDETGTTTASTLLPK
MLBr_00810|M.leprae_Br4923 PRVRSGSGARVLTVSDTHTAVYLPGEAGTQPRVDVIDETGTTVASTLLTK
MAV_4160|M.avium_104 PGIAPDSGARVLAVREATTAVYLPA---PRPRVDVIDETGTTVSSTPLPR
MAB_3532|M.abscessus_ATCC_1997 PGVERGSAAKVLAVADTRSAVYLPG---TRNELVVFDDRGMRVGATVLPG
:.*:*: * . :*:*:* . : :.*: * :* :
Mflv_4677|M.gilvum_PYR-GCK PPSPEATMSKAGDLVTWWTGDALMVFSGNDLRYKYTVAATGPDAPVGPAT
Mvan_1790|M.vanbaalenii_PYR-1 PPSPDATASRVGDLVTWWTGDALMVFSANNLQYKYTVAASGSDAPVGPAT
MSMEG_1929|M.smegmatis_MC2_155 PAAPQSTTTRAGDLVTWWTGDSVMVFDAAGLRYKYTVSPAGPHAPVGPAT
TH_0649|M.thermoresistible__bu PVSPHAATSRTGDLITWWTGESVLVFEAEGLRYRYTVTPSAGATAVGPGV
Mb3238|M.bovis_AF2122/97 PPSTSAVASRTGNLVTWWTGDALLVFDAGNLTQRYTIAAGETTAPVGPGV
Rv3212|M.tuberculosis_H37Rv PPSTSAVASRTGNLVTWWTGDALLVFDAGNLTQRYTIAAGETTAPVGPGV
MMAR_1345|M.marinum_M PPSPAAVVSQTGNLVTWWTGDALLVFNTGKLTQRYTIAAGDTAAPLGPGV
MUL_2534|M.ulcerans_Agy99 PPSPAAVVSQTGNLVTWWTGDALLVFNTGKLTQRYTIAAGDTAAPLGPGV
MLBr_00810|M.leprae_Br4923 PPSSSAVVSQAGNLVTWWTGDTLMVFNQSNLTLRYTIAAGETTAPVGPGV
MAV_4160|M.avium_104 PPSPSAAVSHAGSVMTWWTGDSLMVFDVNTLALRYTIAAGDKTAPLGPGA
MAB_3532|M.abscessus_ATCC_1997 EIAQTNAAAQAGDVITWWTGSQVLVLSASDLSYRFVLPT--TTKPLGPGT
: . ::.*.::*****. ::*:. * ::.:.. .:**..
Mflv_4677|M.gilvum_PYR-GCK IMAGKLLVPVTTGYDVFDPETGTGEKHIPVQRP----PVDGPVVPAVAGT
Mvan_1790|M.vanbaalenii_PYR-1 IMAGQLLVPVTTGYDVFDPMTGTGDKHIPVQRP----QVAGPVVPAVAGS
MSMEG_1929|M.smegmatis_MC2_155 AMAGKLLVPVDDGYDVFDPETGTGDRHISLPRT----PSVSPVVPAVAGS
TH_0649|M.thermoresistible__bu IMADRLMVPVTGGYDVFDPLSGAGERHIPLTRP----QQQSAVFPLVAGT
Mb3238|M.bovis_AF2122/97 MMAGQLLVPVTGGIGVYDPVSGANNRYIPVTRP----PSTSAVIPAVSGS
Rv3212|M.tuberculosis_H37Rv MMAGQLLVPVTGGIGVYDPVSGANNRYIPVTRP----PSTSAVIPAVSGS
MMAR_1345|M.marinum_M MMAGQLLVPVTGALGVYDPVSGASIRYIPVDRQ----PNTSAVIPVVVGS
MUL_2534|M.ulcerans_Agy99 MMAGQVLVPVTGALGVYDPVSGASIRYIPVDRQ----PNTSAVIPVVVGS
MLBr_00810|M.leprae_Br4923 MMAGQLLVPVTGKIGVYDLFSGANNRYIPVRRP----PSSSAVIPAVSGS
MAV_4160|M.avium_104 MMAGRLLVPVTGAIGVYDPISGASERYIPVDRATGGAPPGAAVVPAVSGS
MAB_3532|M.abscessus_ATCC_1997 NMAGELLIPVEGGIDVFNMTTGEFRKSIVVQRN--TADEKSPVISAVVGN
**..:::** .*:: :* : * : * ..*.. * *.
Mflv_4677|M.gilvum_PYR-GCK TVLELRGDDLVALG--
Mvan_1790|M.vanbaalenii_PYR-1 TVLEQRGDELVALG--
MSMEG_1929|M.smegmatis_MC2_155 IVLEQRGTELVALGAA
TH_0649|M.thermoresistible__bu TLVEQRGGVLVALGAG
Mb3238|M.bovis_AF2122/97 RVIEQRGDTLVALG--
Rv3212|M.tuberculosis_H37Rv RVIEQRGDTLVALG--
MMAR_1345|M.marinum_M TVIEQRGDAVVALG--
MUL_2534|M.ulcerans_Agy99 TVIEQRGDAVVALG--
MLBr_00810|M.leprae_Br4923 TVFEQRGDTLVALG--
MAV_4160|M.avium_104 RVFEQRGDTVVALG--
MAB_3532|M.abscessus_ATCC_1997 TLVEQRGSRIFALG--
:.* ** :.***