For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLTIGAVTAAASAGSPLGEHHPHLTPLAQRVLEPTDAA VLAGHDVVFLALPHGHSAALADQLGADTLIVDCGADFRLTDAAAWERFYGAPHAGSWPYGLPELPGARER LRGARRIAVPGCYPTAALLALLPAMAEDLIEPAVTVVAVSGTSGAGRAAKTDLLGSEVIGSARAYNIAGA HRHTPEIAQGLAAVSGRDVTVSFTPVLIPTSRGILATCTARTTAPLSALRAAYEKTYDAEPFIYLMPEGQ LPRTGAVIGSNAAHIAVAVDEAAGVLVAIAAIDNLVKGTAGAAVQSMNLALGWPETQGLSVIGVAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3118 | argC | - | 100% (347) | N-acetyl-gamma-glutamyl-phosphate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1680 | argC | 1e-171 | 85.88% (347) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. gilvum PYR-GCK | Mflv_3530 | argC | 1e-161 | 80.65% (341) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. tuberculosis H37Rv | Rv1652 | argC | 1e-171 | 85.88% (347) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. leprae Br4923 | MLBr_01406 | argC | 1e-161 | 81.56% (347) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. abscessus ATCC 19977 | MAB_2336 | argC | 1e-147 | 74.49% (341) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. marinum M | MMAR_2462 | argC | 1e-175 | 88.41% (345) | N-acetyl-gamma-glutamyl-phosphate reductase ArgC |
| M. smegmatis MC2 155 | MSMEG_3776 | argC | 1e-155 | 78.89% (341) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. thermoresistible (build 8) | TH_1593 | argC | 1e-162 | 80.94% (341) | PROBABLE N-ACETL-GAMMA-GLUTAMYL-PHOSHATE REDUCTASE ARGC |
| M. ulcerans Agy99 | MUL_1644 | argC | 1e-175 | 88.12% (345) | N-acetyl-gamma-glutamyl-phosphate reductase |
| M. vanbaalenii PYR-1 | Mvan_3314 | argC | 1e-163 | 82.99% (341) | N-acetyl-gamma-glutamyl-phosphate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3530|M.gilvum_PYR-GCK ---MHHRGMTTVAVAGASGYAGGEILRLLLGHPAYTDGRLTIGALTAAAS
Mvan_3314|M.vanbaalenii_PYR-1 --------MTSVAVAGASGYAGGEILRLLLGHPAYTDGRLTIGALTAAAS
MSMEG_3776|M.smegmatis_MC2_155 --------MTSIAVAGASGYAGGEILRLLLGHPAYADGRLTIGALTAASS
TH_1593|M.thermoresistible__bu --------MTSVAVAGASGYAGGEILRLLLGHPAYADGRLTIGALTAGAS
Mb1680|M.bovis_AF2122/97 MQNRQVANATKVAVAGASGYAGGEILRLLLGHPAYADGRLRIGALTAATS
Rv1652|M.tuberculosis_H37Rv MQNRQVANATKVAVAGASGYAGGEILRLLLGHPAYADGRLRIGALTAATS
MMAR_2462|M.marinum_M --MAHATDAIRVAVAGASGYAGGEILRLLLGHPAYTSGRLTIGAVTAAAS
MUL_1644|M.ulcerans_Agy99 --MAHATDAIRVAVAGASGYAGGEILRLLLGHPAYTSGRLTIGAVTAAAS
MAV_3118|M.avium_104 -----MADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLTIGAVTAAAS
MLBr_01406|M.leprae_Br4923 -----MSYAIRVAVVGASGYAGGEILRLLLGHPAYADDRLTIGTLTAAAS
MAB_2336|M.abscessus_ATCC_1997 -----MTTGFSVAVAGASGYAGGEILRLLLAHPAYTAGRLRIGVLTAGSN
:**.***************.****: .** **.:**.:.
Mflv_3530|M.gilvum_PYR-GCK AGTSLAEHHPHLLPLADRTLEPTEIGVLAGHDVVFLGLPHGHSAALAEQL
Mvan_3314|M.vanbaalenii_PYR-1 AGSALAEHHPHLLPLADRTLEPTELDVLAGHDVVFLGLPHGHSAALAEQL
MSMEG_3776|M.smegmatis_MC2_155 AGTTLGEHHPHLLPLADRVLESTDVEVLTGHDVVFLALPHGHSAALATQL
TH_1593|M.thermoresistible__bu AGTTLAEHHPHLVPLVDRVLAPTEAEVLSGHDVVFLGLPHGHSAALAEQL
Mb1680|M.bovis_AF2122/97 AGSTLGEHHPHLTPLAHRVVEPTEAAVLGGHDAVFLALPHGHSAVLAQQL
Rv1652|M.tuberculosis_H37Rv AGSTLGEHHPHLTPLAHRVVEPTEAAVLGGHDAVFLALPHGHSAVLAQQL
MMAR_2462|M.marinum_M AGSVLAEHHPHLLPLAQRILEPTELEVLRGHDVVFLALPHGHSAALADQL
MUL_1644|M.ulcerans_Agy99 AGSVLAEHHPHLLPLAQRILEPTELEVLRGHDVVFLALPHGHSAALADQL
MAV_3118|M.avium_104 AGSPLGEHHPHLTPLAQRVLEPTDAAVLAGHDVVFLALPHGHSAALADQL
MLBr_01406|M.leprae_Br4923 SGDTLGEHHPHLTPLAHRVLESTELTVLAGHDVVFLGLPHGHSAALAERL
MAB_2336|M.abscessus_ATCC_1997 AGSSLIEHHPNLTPLADHKLQPTDSTLLRGHDVVFLALPHGSSAKIAEEL
:* * ****:* **..: : .*: :* ***.***.**** ** :* .*
Mflv_3530|M.gilvum_PYR-GCK GPDTLIIDCGADFRLTDAGDWQRFYGSEHAGSWPYGLPELPGGRERLRDT
Mvan_3314|M.vanbaalenii_PYR-1 GPDVLVIDCGADFRLTDAEDWRRFYGSEHAGSWPYGLPELPGGRDRLREA
MSMEG_3776|M.smegmatis_MC2_155 G-GTVIIDCGADFRLAEAADWEKFYGSAHAGTWPYGLPELPGGREALKGA
TH_1593|M.thermoresistible__bu GPDTVIIDCGADFRLTDAVDWERFYGSPHVGSWPYGLPELPGARDRLRGA
Mb1680|M.bovis_AF2122/97 SPETLIIDCGADFRLTDAAVWERFYGSSHAGSWPYGLPELPGARDQLRGT
Rv1652|M.tuberculosis_H37Rv SPETLIIDCGADFRLTDAAVWERFYGSSHAGSWPYGLPELPGARDQLRGT
MMAR_2462|M.marinum_M GPETLIIDCGADFRLTDAAAWERFYGSAHSGSWPYGLPELPGARERLRDT
MUL_1644|M.ulcerans_Agy99 GPETLIIDCGADFRLTDAAAWERFYGSAHSGSWPYGLPELPGARERLRDT
MAV_3118|M.avium_104 GADTLIVDCGADFRLTDAAAWERFYGAPHAGSWPYGLPELPGARERLRGA
MLBr_01406|M.leprae_Br4923 GPETLIIDCGADFRLTDAGAWGRFYESPYAGSWPYGLPELPGGRERLQKA
MAB_2336|M.abscessus_ATCC_1997 GPQTLIIDCGADFRLTDAAAWERYYGSKHAGSWPYGLPELPGGRDALHGT
. .:::********::* * ::* : : *:**********.*: *: :
Mflv_3530|M.gilvum_PYR-GCK KRVAVPGCYPTAALLALWPALAAGLVEPAVTIVAVSGTSGAGRAAKVDLL
Mvan_3314|M.vanbaalenii_PYR-1 RRIAVPGCYPTAALLALWPALAEGLVEPAVTVVAVSGTSGAGKSAKVDLL
MSMEG_3776|M.smegmatis_MC2_155 TRIAVPGCYPTSALLALLPAVAAGLVEPNVTVVAVSGTSGAGKSAKVDLL
TH_1593|M.thermoresistible__bu HRIAVPGCYPTAALLALLPAVAENLVDPAVTVVAVSGTSGAGRVAKPDLL
Mb1680|M.bovis_AF2122/97 RRIAVPGCYPTAALLALFPALAADLIEPAVTVVAVSGTSGAGRAATTDLL
Rv1652|M.tuberculosis_H37Rv RRIAVPGCYPTAALLALFPALAADLIEPAVTVVAVSGTSGAGRAATTDLL
MMAR_2462|M.marinum_M RRIAVPGCYPTAALLALLPAVAEGLIDPAVTVVAVSGTSGAGRAAKTDLL
MUL_1644|M.ulcerans_Agy99 RRIAVPGCYPTAALLALLPAVAEGLIDPAVTVVAVSGTSGAGRAAKTDLL
MAV_3118|M.avium_104 RRIAVPGCYPTAALLALLPAMAEDLIEPAVTVVAVSGTSGAGRAAKTDLL
MLBr_01406|M.leprae_Br4923 RRIAVPGCYPTAILLALLPAMAEGLIEPAVTVFAVSGISGAGRAAKTKLL
MAB_2336|M.abscessus_ATCC_1997 KRVAVPGCYPTAALLALSPAVTAGLVEPSVTVVAVSGTTGAGRAPKAELL
*:********: **** **:: .*::* **:.**** :***: .. .**
Mflv_3530|M.gilvum_PYR-GCK GAEVIGSARAYNIGGKHRHTPEIAQGLRAVSGSAVTVSFTPVLIPTSRGI
Mvan_3314|M.vanbaalenii_PYR-1 GSEVIGSARAYNIGGKHRHTPEIAQGLRAVTGGDVTVSFTPVLIPTSRGI
MSMEG_3776|M.smegmatis_MC2_155 GAEVIGSARAYNVGGKHRHTPEIAQGLRKVTDKPVTVSFTPVLIPTSRGI
TH_1593|M.thermoresistible__bu GAEVIGSARAYNVGGKHRHTPEIAQGLRAVTDREVTVSFTPVLIPTSRGI
Mb1680|M.bovis_AF2122/97 GAEVIGSARAYNIAGVHRHTPEIAQGLRAVTDRDVSVSFTPVLIPASRGI
Rv1652|M.tuberculosis_H37Rv GAEVIGSARAYNIAGVHRHTPEIAQGLRAVTDRDVSVSFTPVLIPASRGI
MMAR_2462|M.marinum_M GSEVIGSARAYNIAGAHRHTPEIAQGLRAVTDRDVTVSFTPVLIPTSRGI
MUL_1644|M.ulcerans_Agy99 GSEVIGSARAYNIAGAHRHTPEIAQGLRAVTDRDVTVSFTPVLIPTSRGI
MAV_3118|M.avium_104 GSEVIGSARAYNIAGAHRHTPEIAQGLAAVSGRDVTVSFTPVLIPTSRGI
MLBr_01406|M.leprae_Br4923 GSEVIGSARAYNIGGTHRHTAEIIQGLRVVTDRAVTVSFTPVLIPTSRGI
MAB_2336|M.abscessus_ATCC_1997 ASEVMGSARAYNIAGAHRHTPEIAQGLKHPSGGPVSVSFTPVLIPMPRGI
.:**:*******:.* ****.** *** :. *:********* .***
Mflv_3530|M.gilvum_PYR-GCK LATCTARTDAPVSEIRAAYEKAYADEPFVYLLPDGRLPKTGAVAGSNAAQ
Mvan_3314|M.vanbaalenii_PYR-1 LATCTARTDATVSQLRAAYEKVYTDEPFVYLLPEGQLPKTGAVIGSNAAQ
MSMEG_3776|M.smegmatis_MC2_155 LATCTAPTTATEPEIRAAYEKAYGAEPFIHLLPEGQLPKTGSVIGSNAAQ
TH_1593|M.thermoresistible__bu LATCTAPTTASPAEFRAAYEKAYADEPFVFVLPDGQLPKTGAVLGSNAAH
Mb1680|M.bovis_AF2122/97 LATCTARTRSPLSQLRAAYEKAYHAEPFIYLMPEGQLPRTGAVIGSNAAH
Rv1652|M.tuberculosis_H37Rv LATCTARTRSPLSQLRAAYEKAYHAEPFIYLMPEGQLPRTGAVIGSNAAH
MMAR_2462|M.marinum_M LATCTARTRSPIARLRSAYEKAYEAEPFIYLMPEGQLPRTGAVIGSNAAH
MUL_1644|M.ulcerans_Agy99 LATCTARTRSPIARLRSAYEKAYEAEPFIYLMPEGQLPRTGAVIGSNAAH
MAV_3118|M.avium_104 LATCTARTTAPLSALRAAYEKTYDAEPFIYLMPEGQLPRTGAVIGSNAAH
MLBr_01406|M.leprae_Br4923 LAACTARTSSSLSKLRTAYEKAYQVEPFVYLMPEGQLPFTGAVIGSNAAH
MAB_2336|M.abscessus_ATCC_1997 LATCTAPTTASLSEIRDAYEDAYRTEEFIHVLPEGHLPTTKAVVGSNAVH
**:*** * :. . :* ***..* * *:.::*:*:** * :* ****.:
Mflv_3530|M.gilvum_PYR-GCK LAIAVDEDASTFLAIAAIDNLVKGTGGAAVQSMNLALGWPEAEGLSTVGL
Mvan_3314|M.vanbaalenii_PYR-1 LAIAVDEDASTFVAIAAIDNLVKGTGGAAVQSMNLALGWPETDGLSIVGV
MSMEG_3776|M.smegmatis_MC2_155 IQIAVDTEAKTLVAICAIDNLTKGTGGAAVQSMNLALGWPETEGLSIVGV
TH_1593|M.thermoresistible__bu IGIAVDTDARTFVAIAAIDNLVKGTGGAAVQSMNLALGWPETEGLTVVGV
Mb1680|M.bovis_AF2122/97 IAVAVDEDAQTFVAIAAIDNLVKGTAGAAVQSMNLALGWPETDGLSVVGV
Rv1652|M.tuberculosis_H37Rv IAVAVDEDAQTFVAIAAIDNLVKGTAGAAVQSMNLALGWPETDGLSVVGV
MMAR_2462|M.marinum_M IAVAVDEEAETFVAIAAIDNLVKGTAGAAVQSMNLALGWPETEGLSVVGV
MUL_1644|M.ulcerans_Agy99 IAIAVDEEAETFVAIAAIDNLVKGTAGAAVQSMNLALGWPETEGLSVVGV
MAV_3118|M.avium_104 IAVAVDEAAGVLVAIAAIDNLVKGTAGAAVQSMNLALGWPETQGLSVIGV
MLBr_01406|M.leprae_Br4923 IAVAVDEAAETFIAISAIDNLVKGTAGAAVQSMNLALGWPEAEGLSVVGV
MAB_2336|M.abscessus_ATCC_1997 IGLAVDPDAGVLVAVAAIDNLVKGTAGAAIQSMNLALGWPEADGLSIVGV
: :*** * .::*:.*****.***.***:***********::**: :*:
Mflv_3530|M.gilvum_PYR-GCK AP
Mvan_3314|M.vanbaalenii_PYR-1 AP
MSMEG_3776|M.smegmatis_MC2_155 AP
TH_1593|M.thermoresistible__bu AP
Mb1680|M.bovis_AF2122/97 AP
Rv1652|M.tuberculosis_H37Rv AP
MMAR_2462|M.marinum_M AP
MUL_1644|M.ulcerans_Agy99 AP
MAV_3118|M.avium_104 AP
MLBr_01406|M.leprae_Br4923 AP
MAB_2336|M.abscessus_ATCC_1997 AP
**