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TVEGDRSSAATGRAPAQGRPRGEAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNT VSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPS AVFYMNKIAVGPEAAHVLDITAPIAENIKAVAKVKALSVRDMTVCILDRPRHAKLIDEVRETGARIRLIT DGDVAGAISACRPHSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDEERQKAIDAGYDLDQILT TEDLVSGENVFFCATGVTNGDLLKGVQYYPGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGD SSAAYPLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1222 | glpX | - | 100% (359) | fructose 1,6-bisphosphatase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1129c | glpX | 1e-177 | 92.99% (328) | fructose 1,6-bisphosphatase II |
| M. gilvum PYR-GCK | Mflv_2066 | glpX | 1e-169 | 85.50% (338) | fructose 1,6-bisphosphatase II |
| M. tuberculosis H37Rv | Rv1099c | glpX | 1e-177 | 92.99% (328) | fructose 1,6-bisphosphatase II |
| M. leprae Br4923 | MLBr_01946 | glpX | 1e-176 | 92.68% (328) | fructose 1,6-bisphosphatase II |
| M. abscessus ATCC 19977 | MAB_1251c | glpX | 1e-158 | 85.49% (317) | fructose 1,6-bisphosphatase II |
| M. marinum M | MMAR_4367 | glpX | 0.0 | 89.78% (362) | fructose 1,6-bisphosphatase GlpX |
| M. smegmatis MC2 155 | MSMEG_5239 | glpX | 1e-171 | 87.57% (338) | fructose 1,6-bisphosphatase II |
| M. thermoresistible (build 8) | TH_0560 | - | 1e-154 | 82.65% (317) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0180 | glpX | 0.0 | 89.23% (362) | fructose 1,6-bisphosphatase II |
| M. vanbaalenii PYR-1 | Mvan_4648 | glpX | 1e-175 | 89.05% (338) | fructose 1,6-bisphosphatase II |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1129c|M.bovis_AF2122/97 ----------------------------------MELVRVTEAGAMAAGR
Rv1099c|M.tuberculosis_H37Rv ----------------------------------MELVRVTEAGAMAAGR
MMAR_4367|M.marinum_M MTAQGSGSSPTAVAGRDPSLPRPPRGEAPDRNLAMELVRVTEAGAMAAGR
MUL_0180|M.ulcerans_Agy99 MTAQGSGSSPTAVAGRDPSLPRPPRGEAPDRNLAMELVRVTEAGAMAAGR
MLBr_01946|M.leprae_Br4923 ----------------------------------MELVRVTEAGAMAAGR
MAV_1222|M.avium_104 MTVEGDRSS--AATGRAPAQGRP-RGEAPDRNLALELVRVTEAGAMAAGR
Mflv_2066|M.gilvum_PYR-GCK --------------------MSASRREAPDRNLALELVRVTEAGAMAAGR
MSMEG_5239|M.smegmatis_MC2_155 --------------------MTPSRGEAPDRNLALELVRVTEAGAMAAGR
Mvan_4648|M.vanbaalenii_PYR-1 --------------------MSSSRREAPDRNLALELVRVTEAGAMAAGR
MAB_1251c|M.abscessus_ATCC_199 ---------------------------------------------MAAGR
TH_0560|M.thermoresistible__bu ---------------------------------------------MAAGR
*****
Mb1129c|M.bovis_AF2122/97 WVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEV
Rv1099c|M.tuberculosis_H37Rv WVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEV
MMAR_4367|M.marinum_M WVGRGDKEGGDAAAVDAIRELVNSVSMRGVVVIGEGEKDDAPMLYNGEDV
MUL_0180|M.ulcerans_Agy99 WVGRGDKEGGDAAAVDAIRELVNSVSMRGVVVIGEGEKDDAPMLYNGEDV
MLBr_01946|M.leprae_Br4923 WVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPMLYNGEEV
MAV_1222|M.avium_104 WVGRGDKEGGDGAAVDAMRELVNTVSMRGVVVIGEGEKDHAPMLYNGEEV
Mflv_2066|M.gilvum_PYR-GCK WVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDNAPMLYNGEEV
MSMEG_5239|M.smegmatis_MC2_155 WVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDNAPMLYNGEEV
Mvan_4648|M.vanbaalenii_PYR-1 WVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDNAPMLYNGEEV
MAB_1251c|M.abscessus_ATCC_199 WVGRGEKEKGDGAAVDAMRELVNSVSMRGVVVIGEGEKDNAPMLYNGEEV
TH_0560|M.thermoresistible__bu WVGRGDKEGGDAAAVDAMRSLVNTVSMRGVVVIGEGEKDNAPMLYNGEEV
*****:** **.****::*.***:***************.********:*
Mb1129c|M.bovis_AF2122/97 GNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMN
Rv1099c|M.tuberculosis_H37Rv GNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMN
MMAR_4367|M.marinum_M GNGDGPECDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMN
MUL_0180|M.ulcerans_Agy99 GNGDGPECDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMS
MLBr_01946|M.leprae_Br4923 GNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMN
MAV_1222|M.avium_104 GNGDGPECDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMN
Mflv_2066|M.gilvum_PYR-GCK GNGDGPDCDFAVDPVDGTTLMSKGMPNAISVLAVAERGAMFDPSAVFYMN
MSMEG_5239|M.smegmatis_MC2_155 GNGDGPECDFAVDPIDGTTLMSKGMPNAISVLAVAERGAMFDPSAVFYMN
Mvan_4648|M.vanbaalenii_PYR-1 GNGDGPDCDFAVDPVDGTTLMSKGMPNAISVLAVAERGAMFDPSAVFYMH
MAB_1251c|M.abscessus_ATCC_199 GNGDGPDCDFAVDPVDGTTLMSKGMPNAISVLAVSERGAMFDPSAVFYME
TH_0560|M.thermoresistible__bu GNGDGPECDFAVDPIDGTTLMSKGRPDAISVLAVSDRGTMFDPSAVFYMN
******:*******:********* .:*******::**:**********
Mb1129c|M.bovis_AF2122/97 KIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLI
Rv1099c|M.tuberculosis_H37Rv KIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLI
MMAR_4367|M.marinum_M KIAVGPEAAHVLDITAPIAENVRAVARVKALSARDMTVCILDRPRHAQLI
MUL_0180|M.ulcerans_Agy99 KIAVGPEAAHVLDITAPIAENVRAVARVKALSARDMTVCILDRPRHAQLI
MLBr_01946|M.leprae_Br4923 KITVGPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRPRHAQLI
MAV_1222|M.avium_104 KIAVGPEAAHVLDITAPIAENIKAVAKVKALSVRDMTVCILDRPRHAKLI
Mflv_2066|M.gilvum_PYR-GCK KIAGGPDVAEFIDITSPIAANIQRIAKVRKASVSDVTVCILDRPRHAKLM
MSMEG_5239|M.smegmatis_MC2_155 KIAAGPDVADFIDITSPIAANIQRIAKMRKASVSDITVCILDRPRHAKLI
Mvan_4648|M.vanbaalenii_PYR-1 KIAVGPDAADVIDITAPIAENIRQVAKVKNSSVRDLTVCILDRPRHQQLM
MAB_1251c|M.abscessus_ATCC_199 KIAVGPDAADVIDITAPVSENIKRVAKVRSCSVSDITVCILDRPRHGELI
TH_0560|M.thermoresistible__bu KIAVGPDAVDAIDITAPIGENIRKVAKAKKMSVSDLTVCILDRPRHAELI
**: **:... :***:*:. *:: :*: : *. *:********** :*:
Mb1129c|M.bovis_AF2122/97 HDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAI
Rv1099c|M.tuberculosis_H37Rv HDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAI
MMAR_4367|M.marinum_M EDVRATGARIRLITDGDVAGAISACRPESGTDMLAGIGGTPEGIIAAAAI
MUL_0180|M.ulcerans_Agy99 EDVRATGARIRLITDGDVAGAISACRPESGTDMLAGIGGTPEGIIAAAAI
MLBr_01946|M.leprae_Br4923 DDVRATGARIRLITDGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAI
MAV_1222|M.avium_104 DEVRETGARIRLITDGDVAGAISACRPHSGTDMLAGIGGTPEGIIAAAAI
Mflv_2066|M.gilvum_PYR-GCK EEVRSAGARIRLISDGDVAGAISACRPESGTDLLVGIGGTPEGIIAAAAI
MSMEG_5239|M.smegmatis_MC2_155 ADVRAAGARIRLISDGDVAGAISACRPDSGTDLLAGIGGTPEGIITAAAI
Mvan_4648|M.vanbaalenii_PYR-1 ADVREAGARIRLISDGDVAGAISACRPNSGTDMLVGIGGTPEGIIAAAAI
MAB_1251c|M.abscessus_ATCC_199 QNVRETGARIRLISDGDVAGAISTARPNSGTDMLLGIGGTPEGIIAAAAM
TH_0560|M.thermoresistible__bu AQVREAGARCRLITDGDVAGAIATCRPSTPTDLLVGIGGTPEGIIAAAAI
:** :*** ***:********::.** : **:* **********:***:
Mb1129c|M.bovis_AF2122/97 RCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATG
Rv1099c|M.tuberculosis_H37Rv RCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATG
MMAR_4367|M.marinum_M RCMGGAIQAQLAPKDEAERRKALDAGYDLDQVLTTEDLVSGENVFFCATG
MUL_0180|M.ulcerans_Agy99 RCMGGAIQAQLAPKDEAERRKALDVGYDLDQVLTTEDLVSGENVFFCATG
MLBr_01946|M.leprae_Br4923 RCMGGAIQAQLAPRDDVERRKALDAGYNLDRILTTEDLVSGENVFFCATG
MAV_1222|M.avium_104 RCMGGAIQAQLAPRDDEERQKAIDAGYDLDQILTTEDLVSGENVFFCATG
Mflv_2066|M.gilvum_PYR-GCK RCMGGEIQATLAPTDDEERQRAIDRGHDLDRVLTTRDLVSGENVFFCATG
MSMEG_5239|M.smegmatis_MC2_155 RCMGGEIQATLAPTDDEERQKAIDRGHDLDRVLTTKDLVSGENVFFCATG
Mvan_4648|M.vanbaalenii_PYR-1 RCMGGAIQAKLAPTDDAERQKALDRGHDLDRVLTTEDLVSGENVFFCATG
MAB_1251c|M.abscessus_ATCC_199 RCMGGAIHGKLAPRDDEERQKAIDAGYDLDQILTTEDLVSGENVFFCATG
TH_0560|M.thermoresistible__bu RCMGGAIQGQLWPKDDEEKQRAIDRGHDVDRVLTTEDLVSGDNVFFAATG
***** *:. * * *: *:::*:: *::::::***.*****:****.***
Mb1129c|M.bovis_AF2122/97 VTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAID
Rv1099c|M.tuberculosis_H37Rv VTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAID
MMAR_4367|M.marinum_M VTDGDLLKGVRYYPGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAID
MUL_0180|M.ulcerans_Agy99 VTDGDLLKGVRYYPGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAID
MLBr_01946|M.leprae_Br4923 VTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAID
MAV_1222|M.avium_104 VTNGDLLKGVQYYPGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAID
Mflv_2066|M.gilvum_PYR-GCK VTDGDLLKGVRFFGGGCTTQSIVMRSKSGTVRMIDAYHRLSKLNEYSAVN
MSMEG_5239|M.smegmatis_MC2_155 VTDGDLLKGVRFFGGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIN
Mvan_4648|M.vanbaalenii_PYR-1 VTDGDLLKGVQYYGGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAVD
MAB_1251c|M.abscessus_ATCC_199 VTDGDLLQGVRYFGGGCTTQSIVMRSKSGTVRMIEAYHRLTKLREYSAVD
TH_0560|M.thermoresistible__bu VTDGELLKGVHYYPGGCTTQSIVMRSKSGTVRMIDAYHRLSKLNEYAAIE
**:*:**:**::: *****:**************:*****:**.**:*::
Mb1129c|M.bovis_AF2122/97 FTGDSSAVYPLP
Rv1099c|M.tuberculosis_H37Rv FTGDSSAVYPLP
MMAR_4367|M.marinum_M FTGDSTAAYPLP
MUL_0180|M.ulcerans_Agy99 FTGDSTAAYPLP
MLBr_01946|M.leprae_Br4923 FTGDNNAAYPLP
MAV_1222|M.avium_104 FTGDSSAAYPLP
Mflv_2066|M.gilvum_PYR-GCK FTGDKTAAYPLP
MSMEG_5239|M.smegmatis_MC2_155 FTGDSSAAYPLP
Mvan_4648|M.vanbaalenii_PYR-1 FTGDKTAAYPLP
MAB_1251c|M.abscessus_ATCC_199 FMGDDDATHPLP
TH_0560|M.thermoresistible__bu YTGDADAIQPLP
: ** * ***