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M. avium 104 MAV_1133 (-)

annotation: methyltransferase FkbM
coordinates: 1073515 - 1074309
length: 264

ALARSAKRWLAPAAKRLAPRRFWRRKFRILDRLGRSRPDVQLVASLCDPHRVSLDIGADLGEFTIAMAAS
SRSVIAFEPRPAQARDLAAMFDAVGAAVRVEAVALSDEPGTIAMRVVESEPGRSTIDTDNSLGDLTGDQI
RVIDVPVKRLDDLNLDDVGLVKIDVEGHELAVLRGAAETLARNRPAIVVEAEERHHRGAVAGITRLLTGL
GYSGYFELDGARRPIAEFDPALHQDPANAGSRQDGWTGRGPYVNNFVFLPDER*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1133--100% (264)methyltransferase FkbM

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2979c-8e-1434.42% (215) hypothetical protein Mb2979c
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2955c-9e-1434.42% (215) hypothetical protein Rv2955c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2973c-2e-1133.51% (185) putative methyltransferase
M. marinum MMMAR_4517-1e-10873.95% (261) hypothetical protein MMAR_4517
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4688-1e-10672.80% (261) hypothetical protein MUL_4688
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb2979c|M.bovis_AF2122/97           MQFQDVRLMRVVVCRRLGPAKGQRRWHPLDLGTTGCFENLGAQRPTYRMR
Rv2955c|M.tuberculosis_H37Rv        MQFQDVRLMRVVVCRRLGPAKGQRRWRPLDLGTTGCFENLGAQRPTYRMR
MMAR_4517|M.marinum_M               --------------------------------------------------
MUL_4688|M.ulcerans_Agy99           --------------------------------------------------
MAV_1133|M.avium_104                --------------------------------------------------
MAB_2973c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2979c|M.bovis_AF2122/97           AIRMLECAMPNRLVRSLQRWRPFGLPPHRWRLAP-WYWRGLQVTLEPGSA
Rv2955c|M.tuberculosis_H37Rv        AIRMLECAMPNRLVRSLQRWRPFGLPPHRWRLAP-WYWRGLQVTLEPGSA
MMAR_4517|M.marinum_M               ----------MTAAARTKRW----LAPVVRTVAPVLFWQRKYRVLQR---
MUL_4688|M.ulcerans_Agy99           ----------MTAAARIKRW----LAPVVRTVAPGLFWQRKYRVLQR---
MAV_1133|M.avium_104                ----------MALARSAKRW----LAPAAKRLAPRRFWRRKFRILDR---
MAB_2973c|M.abscessus_ATCC_199      ---------MTRRVTAFGEIRDAVVGQGLRTLARTTPWVESELVGIAQVV
                                                 .    .     :      :*    *            

Mb2979c|M.bovis_AF2122/97           IAWIVRLTGGFEETEIDIAAALYSALYPDRCILDVGANVGIHSLAWARLA
Rv2955c|M.tuberculosis_H37Rv        IAWIVRLTGGFEETEIDIAAALYSALYPDRCILDVGANVGIHSLAWARLA
MMAR_4517|M.marinum_M               --------LGESRADVRLAASLCD---PDRISVDIGADVGEFTIAMLASS
MUL_4688|M.ulcerans_Agy99           --------LGESRADVRLAASLCD---PDRISVDIGADVGEFTIAMLASS
MAV_1133|M.avium_104                --------LGRSRPDVQLVASLCD---PHRVSLDIGADLGEFTIAMAASS
MAB_2973c|M.abscessus_ATCC_199      R-------TGDVCIDVGAAAGFYT----AELARLVGAEGLVYSLEPLRFA
                                             *    ::  .*.:       .    :**:   .::     :

Mb2979c|M.bovis_AF2122/97           P-VVALEPAPGTHSRLEANVAANGLQDRIRTLRTAAGDAVGEVDFFVAAD
Rv2955c|M.tuberculosis_H37Rv        P-VVALEPAPGTHSRLEANVAANGLQDRIRTLRTAAGDAVGEVDFFVAAD
MMAR_4517|M.marinum_M               RSVVAFEPRPAQARELASMFHAVGAAVRVEAV--ALSDKPGCLSMRVVES
MUL_4688|M.ulcerans_Agy99           HSVVAFEPRPAQARELASMFDAVGAAVRVEAV--ALSDKPGCLSMRVVES
MAV_1133|M.avium_104                RSVIAFEPRPAQARDLAAMFDAVGAAVRVEAV--ALSDEPGTIAMRVVES
MAB_2973c|M.abscessus_ATCC_199      HATSSAALGLRSAQNVRRHAVALGTNTGEQVMSVPLRNGKPITGRSFVDA
                                      . :          :     * *     ..:  .  :        ..  

Mb2979c|M.bovis_AF2122/97           SAFSSLNDTGRIR---IRERTRVPCTTLDALAAELPLPVGLLKIDVEGLE
Rv2955c|M.tuberculosis_H37Rv        SAFSSLNDTGRIR---IRERTRVPCTTLDALAAELPLPVGLLKIDVEGLE
MMAR_4517|M.marinum_M               EPGRSTIDTDNALGDVAG-RIRSIDVAVKRLDDLQLSDVGLIKVDVEGHE
MUL_4688|M.ulcerans_Agy99           EPGRSTIDTDNALGDVAG-RIRSIDVAVKRLDDLQLSDVGLIKVDVEGHE
MAV_1133|M.avium_104                EPGRSTIDTDNSLGDLTGDQIRVIDVPVKRLDDLNLDDVGLVKIDVEGHE
MAB_2973c|M.abscessus_ATCC_199      GADGLGSNAEFDEHIRVVVDTETFDGFCERLN---ISRIDFVKIDVEGAE
                                     .     ::            .      . *       :.::*:**** *

Mb2979c|M.bovis_AF2122/97           RAVIAGAAELLRRDRPVLLVEIYGGAASNPDPERT-------------IA
Rv2955c|M.tuberculosis_H37Rv        RAVIAGAAELLRRDRPVLLVEIYGGAASNPDPERT-------------IA
MMAR_4517|M.marinum_M               LAVLRGATDTLIRNRPTILVEAEERHHPNAVAEITTLLGGLGYRGFFELG
MUL_4688|M.ulcerans_Agy99           LAVLRGATDTLMRNRPTILVEAEERHRPNAVAEITTLLGGLGYRGFFELG
MAV_1133|M.avium_104                LAVLRGAAETLARNRPAIVVEAEERHHRGAVAGITRLLTGLGYSGYFELD
MAB_2973c|M.abscessus_ATCC_199      LDVLVSGEKTIERTRPAMMLEVEDRHMERFG------------------R
                                      *: .. . : * **.:::*                             

Mb2979c|M.bovis_AF2122/97           DIR--AYGYEPFVYADDAGLQPYQRHRDDR----YCYFFIPSRKG
Rv2955c|M.tuberculosis_H37Rv        DIR--AYGYEPFVYADDAGLQPYQRHRDDR----YCYFFIPSRKG
MMAR_4517|M.marinum_M               DARRPIAEFDVALHQNPANIGGQRDGWAPRGVYVNNFVFVP----
MUL_4688|M.ulcerans_Agy99           DERRPIAEFDVARHQNPANIGGQRDGWAPRGVYVNNFVFVP----
MAV_1133|M.avium_104                GARRPIAEFDPALHQDPANAGSRQDGWTGRGPYVNNFVFLPDER-
MAB_2973c|M.abscessus_ATCC_199      TAEDIVAWFTARDYRMSVWSAESWRPVDKVTETFRNYLFQPR---
                                      .     :    :   .                  :.* *