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RIGPIELASPVVLAPMAGVTNVAFRTLCRELERELVGTVSGLYVCEMVTARALVERHPATMHMTTFAPDE SPRSLQLYTVDPATTYAAAKMIANEGLADHIDMNFGCPVPKVTKRGGGSALPYKRRLFGQIVAAAVRATQ GTEIPVTVKFRIGIDEEHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIALLKQQVRTIPVLG NGDIYDASDALTMMAATGCDGVVIGRGCLGRPWLFAELSAAFTGSPPPTPPTLGQVADIVRRHGRLLAAH FGEDKGMRDIRKHIAWYLHGFPAGSELRRALAIVKTLDELDRLLDRLDGSVPFPDEATGPRGRQGSPARV VLPEGWLDDPDDCTVPAGADVMHSGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0771 | - | - | 100% (377) | dihydrouridine synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0846c | - | 0.0 | 88.86% (377) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1667 | - | 0.0 | 84.08% (377) | nifR3 family TIM-barrel protein |
| M. tuberculosis H37Rv | Rv0823c | - | 0.0 | 88.86% (377) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02186 | - | 0.0 | 83.59% (384) | transcriptional regulator (NifR3/Smm1 family) |
| M. abscessus ATCC 19977 | MAB_0753c | - | 1e-179 | 78.78% (377) | tRNA-dihydrouridine synthase |
| M. marinum M | MMAR_4857 | - | 0.0 | 89.66% (377) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5774 | - | 0.0 | 84.62% (377) | tRNA-dihydrouridine synthase, putative |
| M. thermoresistible (build 8) | TH_1578 | - | 0.0 | 83.82% (377) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_0444 | - | 0.0 | 88.86% (377) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5086 | - | 0.0 | 84.62% (377) | nifR3 family TIM-barrel protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1667|M.gilvum_PYR-GCK MAHLRTRGLQRRERPDARRDRRARRGAAGDGPEVRDRQAAPRGAAASDGR
Mvan_5086|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5774|M.smegmatis_MC2_155 --------------------------------------------------
TH_1578|M.thermoresistible__bu --------------------------------------------------
MAB_0753c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0846c|M.bovis_AF2122/97 --------------------------------------------------
Rv0823c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4857|M.marinum_M --------------------------------------------------
MUL_0444|M.ulcerans_Agy99 --------------------------------------------------
MAV_0771|M.avium_104 --------------------------------------------------
MLBr_02186|M.leprae_Br4923 --------------------------------------------------
Mflv_1667|M.gilvum_PYR-GCK EEGRQESAGGIISLVTDTPGCEGRTARSLRIGPFDLRSPVVLAPMAGVTN
Mvan_5086|M.vanbaalenii_PYR-1 ----------------------------MRIGPIALHSPVVLAPMAGVTN
MSMEG_5774|M.smegmatis_MC2_155 -----------MSLTALDP-----ARSALQIGSIALHSPVVLAPMAGVTN
TH_1578|M.thermoresistible__bu -----------MTVAADTR--------PLRIGSIELASPVVLAPMAGVTN
MAB_0753c|M.abscessus_ATCC_199 -----------MTASVDLP---EARSRELRIGSLALPSPVVLAPMAGVTN
Mb0846c|M.bovis_AF2122/97 ----------------MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTN
Rv0823c|M.tuberculosis_H37Rv ----------------MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTN
MMAR_4857|M.marinum_M ----------------------------MRIGPIELASPVVLAPMAGVTN
MUL_0444|M.ulcerans_Agy99 ----------------------------MRIGPIELASPVALAPMAGVTN
MAV_0771|M.avium_104 ----------------------------MRIGPIELASPVVLAPMAGVTN
MLBr_02186|M.leprae_Br4923 ----------------------------------------MLAPMAGVTN
*********
Mflv_1667|M.gilvum_PYR-GCK VAFRTLCREL-------------------ELSRAGTVSGLYVCEMVTARA
Mvan_5086|M.vanbaalenii_PYR-1 VAFRTLCREL-------------------ELSRAGTVSGLYVCEMVTARA
MSMEG_5774|M.smegmatis_MC2_155 VAFRTLCREL-------------------EIARAGTVSGLYVCEMVTARA
TH_1578|M.thermoresistible__bu VAFRTLCREL-------------------EIARAGTVSGLYVCEMVTARA
MAB_0753c|M.abscessus_ATCC_199 VAFRTLCREL-------------------ELATTGTVSGLYVCEMVTARA
Mb0846c|M.bovis_AF2122/97 VAFRALCRQL-------------------EQSKVGTVSGLYVCEMVTARA
Rv0823c|M.tuberculosis_H37Rv VAFRALCRQL-------------------EQSKVGTVSGLYVCEMVTARA
MMAR_4857|M.marinum_M VAFRTLCREL-------------------EQAKVGTVSGLYVCEMVTARA
MUL_0444|M.ulcerans_Agy99 VAFRTLCREL-------------------EEAKVGTVSGLYVCEMVTARA
MAV_0771|M.avium_104 VAFRTLCREL-------------------ERELVGTVSGLYVCEMVTARA
MLBr_02186|M.leprae_Br4923 VTFRTLCREFGSTRGNLLRPAPPHLRSPLEQSQVGTISGLYVCEMVTARA
*:**:***:: * .**:*************
Mflv_1667|M.gilvum_PYR-GCK LVERHPVTMHMTTFAPEESPRSLQLYTVDPVNTYAAAKMIVDENLADHID
Mvan_5086|M.vanbaalenii_PYR-1 LVERHPVTMHMTTFAPEESPRSLQLYTVDPANTYAAAKMIVDENLADHID
MSMEG_5774|M.smegmatis_MC2_155 LVERHPVTMHMTTFAPEESPRSLQLYTVDPENTYKAAKMIVDEDLADHID
TH_1578|M.thermoresistible__bu LVERHPATMHMTTFGPSETPRSLQLYSVDPDYTYRAAKMIADENLADHID
MAB_0753c|M.abscessus_ATCC_199 LAERHPVTLHMTTFSPEESPRSLQLYSVDPETTYRAAKMVVDEGLADHID
Mb0846c|M.bovis_AF2122/97 LIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHID
Rv0823c|M.tuberculosis_H37Rv LIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHID
MMAR_4857|M.marinum_M LVERHPVTMHMTTFAPDESPRSLQLYTVDPDTTYAAARMIAEEGLADHID
MUL_0444|M.ulcerans_Agy99 LVERHPVTMHMTTFAPDESPRSLQLYTVDPDTTYAAARMIAEEGLADHID
MAV_0771|M.avium_104 LVERHPATMHMTTFAPDESPRSLQLYTVDPATTYAAAKMIANEGLADHID
MLBr_02186|M.leprae_Br4923 LVERNAVTIHMTTFAPDESPRSLQLYTVDPATTYTAAKMVADEGLADHID
* **:..*:*****...*:*******:*** ** **:*:. *.******
Mflv_1667|M.gilvum_PYR-GCK MNFGCPVPKVTRRGGGAALPYKRRLFGQIVSAAVRATEGTDIPVTVKFRI
Mvan_5086|M.vanbaalenii_PYR-1 MNFGCPVPKVTRRGGGAALPYKRRLFGQIIRAAVAATEGTDIPVTVKFRI
MSMEG_5774|M.smegmatis_MC2_155 MNFGCPVPKVTKRGGGAALPYKRRLFGQIVAAAVRATEGTDIPVTVKFRI
TH_1578|M.thermoresistible__bu MNFGCPVPKVTRRGGGAALPYKRRLFGRIVAAAVAATEGTGIPVTVKFRV
MAB_0753c|M.abscessus_ATCC_199 MNFGCPVPKVTRNGGGAALPYKRRLFGQIVAAAVRATAGTDIPVTVKFRV
Mb0846c|M.bovis_AF2122/97 MNFGCPVPKVTKRGCGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRI
Rv0823c|M.tuberculosis_H37Rv MNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRI
MMAR_4857|M.marinum_M MNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRGVEGTDIPVTVKFRI
MUL_0444|M.ulcerans_Agy99 MNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRGVEGTDIPVTVKFRI
MAV_0771|M.avium_104 MNFGCPVPKVTKRGGGSALPYKRRLFGQIVAAAVRATQGTEIPVTVKFRI
MLBr_02186|M.leprae_Br4923 MNFGCPMPKVTRRGGGAALPYKRRLFGQIVAAAVRATEGTKIPVTVKFRI
******:****:.* *:***:******:*: *** .. ** ********:
Mflv_1667|M.gilvum_PYR-GCK GIDDEHHTHLDAGRIAAEEGAAAVALHARTAAQRYSGSADWDQIAALKAH
Mvan_5086|M.vanbaalenii_PYR-1 GIDDAHHTHLDAGRIAADEGAAAVALHARTAAQRYSGSADWEQIAALKAH
MSMEG_5774|M.smegmatis_MC2_155 GIDDEHHTHLDAGRIAAEEGAAAVALHARTAAQRYSGTADWEQIAALKAH
TH_1578|M.thermoresistible__bu GIDDEHHTHLDAGRIAAEEGAAAVALHARTAAQRYSGTADWSQIAALKAH
MAB_0753c|M.abscessus_ATCC_199 GIDDDHHTHLDAGAIAESEGAAAVALHARTASQRYSGTADWSQIAALKNH
Mb0846c|M.bovis_AF2122/97 GIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQH
Rv0823c|M.tuberculosis_H37Rv GIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQH
MMAR_4857|M.marinum_M GIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIALLKQH
MUL_0444|M.ulcerans_Agy99 GIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIALLKQH
MAV_0771|M.avium_104 GIDEEHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIALLKQQ
MLBr_02186|M.leprae_Br4923 GIDDEHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWAQIAQLKQQ
***: ******** ** *************:*****:*** *** ** :
Mflv_1667|M.gilvum_PYR-GCK VTNVPVLGNGDIFDARDALAMMAATGCDGVVIGRGCLGRPWLFAELSAAF
Mvan_5086|M.vanbaalenii_PYR-1 VTNIPVLGNGDIFDARDALAMMAATGCDGVVIGRGCLGRPWLFAELSAAF
MSMEG_5774|M.smegmatis_MC2_155 VTGIPVLGNGDIFEADDALAMMAATGCDGVVIGRGCLGRPWLFAELSAAF
TH_1578|M.thermoresistible__bu VPDIPVLGNGDIFEASDAVAMMAETGCDGVVIGRGCLGRPWLFAELSAAF
MAB_0753c|M.abscessus_ATCC_199 VTTIPVLGNGDIFDAADAVAMMEQTGCDGVVIGRGCLGRPWLFAELSAVF
Mb0846c|M.bovis_AF2122/97 VRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAF
Rv0823c|M.tuberculosis_H37Rv VRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAF
MMAR_4857|M.marinum_M VRTVPVLGNGDIYDASDALAMMAATGCDGVVIGRGCLGRPWLFAELSAAF
MUL_0444|M.ulcerans_Agy99 VRTVPVLGNGDIYDASDALAMIAATGCDGVVIGRGCLGRPWLFAELSAAF
MAV_0771|M.avium_104 VRTIPVLGNGDIYDASDALTMMAATGCDGVVIGRGCLGRPWLFAELSAAF
MLBr_02186|M.leprae_Br4923 VRTIPVLGNGDIYDASDALAMMAVTGCDGVVIGRGCLGRPWLFAELSAAF
* :********::* **::*: ************************.*
Mflv_1667|M.gilvum_PYR-GCK TGATPATPPTLGEVAQIIRRHGELLAAHFGEDKGMRDIRKHVAWYMHGFP
Mvan_5086|M.vanbaalenii_PYR-1 NGTAPATPPTLGEVAQIIRRHGELLAAHFGEDKGMRDIRKHVAWYMHGFP
MSMEG_5774|M.smegmatis_MC2_155 NNRPIPTPPTLGEVADIVRRHGELLSRHFGEDKGMRDIRKHVAWYLHGFP
TH_1578|M.thermoresistible__bu AGRDIPTPPTLGEVAGIIRRHAELLAAHFGEDKGLRDMRKHIAWYLHGFP
MAB_0753c|M.abscessus_ATCC_199 NGQTIPAPPNLGQVTVIMRRHAELLVDHFGEDKALRDMRKHIAWYLHGFP
Mb0846c|M.bovis_AF2122/97 TGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFP
Rv0823c|M.tuberculosis_H37Rv TGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFP
MMAR_4857|M.marinum_M TGNPGPTPPTLGEVTDIIRRHGELLAAHFGEDKGMRDIRKHVAWYLHGFP
MUL_0444|M.ulcerans_Agy99 TGNPGPTPPTLGEVTDIIRRHGELLAAHFGEDKGVRDIRKHVAWYLHGFP
MAV_0771|M.avium_104 TGSPPPTPPTLGQVADIVRRHGRLLAAHFGEDKGMRDIRKHIAWYLHGFP
MLBr_02186|M.leprae_Br4923 TGRPAPAPPTLGEVAEIVRRHGKLLVAHFGEDKGMRDIRKHIAWYLHGFP
. .:**.**:*: *:***. ** ******.:**:***:***:****
Mflv_1667|M.gilvum_PYR-GCK AGADLRRSMALVKTISELDDLLEQLDPDVPFPAAANGPRGRQGSAASVTL
Mvan_5086|M.vanbaalenii_PYR-1 AGADLRRSLALVKTISELDDLLDQLDPDVPFPAAANGPRGRQGSAASVTL
MSMEG_5774|M.smegmatis_MC2_155 AGADLRRALALVKTRRELDELLDQLDRDAPFPPAATGPRGRQGSASSVHL
TH_1578|M.thermoresistible__bu AGAELRRSLALVRTLAELDDLLAQLDPTVPFPPAATGPRGRQGSAASVTL
MAB_0753c|M.abscessus_ATCC_199 AGGDIRRALALVSTRAELDTLLEQLDQSAPFPEGGNGPRGRQGSPAKVSL
Mb0846c|M.bovis_AF2122/97 AGSALRRALAMVKTLDELDCLLDRLDGTVPFPDSATGARGRQGSPARVAL
Rv0823c|M.tuberculosis_H37Rv AGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVAL
MMAR_4857|M.marinum_M AGSDLRRALALVKTLDELDSLLTRLDPDVAFPEAANGPRGRQGSPSRVAL
MUL_0444|M.ulcerans_Agy99 AGSDLRRALALVKTLDELDSLLTRLDPGVAFPEAANGPRGRQGSPSRVAL
MAV_0771|M.avium_104 AGSELRRALAIVKTLDELDRLLDRLDGSVPFPDEATGPRGRQGSPARVVL
MLBr_02186|M.leprae_Br4923 AGSELRNALALVKTLDELDCLLNRLDGAVPFPDAAIGPRGRQGSPAWVAL
**. :*.::*:* * *** ** :** ..** . *.******.: * *
Mflv_1667|M.gilvum_PYR-GCK PEGWLDDPDDCTVPAGADVMHSGG
Mvan_5086|M.vanbaalenii_PYR-1 PEGWLDDPDDCTVPAGADVMHSGG
MSMEG_5774|M.smegmatis_MC2_155 PEGWLDDPDDCAVPVGADVMHSGG
TH_1578|M.thermoresistible__bu PEGWLDDPDDCTVPAGADVMHSGG
MAB_0753c|M.abscessus_ATCC_199 PDGWLNDPDDCTVPSAADVMHSGG
Mb0846c|M.bovis_AF2122/97 PDGWLTDPDDCRVPEGADAMGSGG
Rv0823c|M.tuberculosis_H37Rv PDGWLTDPDDCRVPEGADAMGSGG
MMAR_4857|M.marinum_M PEGWLDDPDDCQVPDGADVMHSGG
MUL_0444|M.ulcerans_Agy99 PEGWLDDPDDCRVPDGADVMHSGG
MAV_0771|M.avium_104 PEGWLDDPDDCTVPAGADVMHSGG
MLBr_02186|M.leprae_Br4923 PDSWLTDPDDCTVPIGADIMESGG
*:.** ***** ** .** * ***