For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_0558 (-)

VEKRLIGAGLLAGAVGAVLAFVFARLCAEPVIARAIAFEDGRADAENAHGVHEHGAELFSRGVQSGPGLG
FGVLIFGLAMGALFAVLFSVVYARTESISPQALSLLLAAGAFGAVYLVPFVKYPPNPPAVGQADTIGART
GWYLALVAASAALTIGVVWLARRLEARLGPWNARLLSAAAYLVAIVAVAVLAPSVDETPAPLRDAAGAIV
YPGFPADVLYEFRLVSLAAQLVLWAGIGLVFAAVSGRLLGARAPRVPA

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_0558	-	-	100% (258)	hypothetical protein MAV_0558
M. avium 104	MAV_3079	-	4e-06	40.59% (101)	HAD-superfamily protein hydrolase, subfamily protein IIA

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_1432	-	3e-66	49.63% (268)	hypothetical protein Mflv_1432
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_0551	-	6e-61	47.43% (253)	hypothetical protein MAB_0551
M. marinum M	MMAR_5097	-	1e-84	64.98% (257)	hypothetical protein MMAR_5097
M. smegmatis MC2 155	MSMEG_6089	-	8e-64	48.88% (268)	hypothetical protein MSMEG_6089
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	MUL_4173	-	8e-84	64.59% (257)	hypothetical protein MUL_4173
M. vanbaalenii PYR-1	Mvan_5355	-	4e-68	52.45% (265)	hypothetical protein Mvan_5355

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5097|M.marinum_M               MPLSRAANVERRLIARGLLAGAVGAVLAFVFARLFAEPIIGRAVEFED--
MUL_4173|M.ulcerans_Agy99           --------MERWLIARGLLAGAVGAVLAFVFARLFAEPIIGRAVEFED--
MAV_0558|M.avium_104                --------MEKRLIGAGLLAGAVGAVLAFVFARLCAEPVIARAIAFED--
Mflv_1432|M.gilvum_PYR-GCK          --------MEKQIIWRGLLAGAVAGVLAFVFARIFVEPQIELAIGYEEGI
Mvan_5355|M.vanbaalenii_PYR-1       --------MEKQIIGRGLLAGAVAGVLAFLFARIFVEPQIQLAIGYEEGV
MSMEG_6089|M.smegmatis_MC2_155      --------MEKHIIGRGLVAGALGGVLAFVWSWIFIEPLINRAIDYEDAV
MAB_0551|M.abscessus_ATCC_1997      --------MEKSIILRGLGFGAVGGLLSFIFGWIFVEPVINRAIAYEDGR
                                            :*: :*  **  **:..:*:*::. :  ** *  *: :*:  

MMAR_5097|M.marinum_M               --ARTEAAH---AHG--VHEHG---AELFSRGVQANAGLGFGVLIFGLAV
MUL_4173|M.ulcerans_Agy99           --ARTEAAH---AHG--VHEHG---AELFSRGVQANAGLGFGVLIFGLAV
MAV_0558|M.avium_104                --GRADAEN---AHG--VHEHG---AELFSRGVQSGPGLGFGVLIFGLAM
Mflv_1432|M.gilvum_PYR-GCK          GAAHEALEHGHGGHGGHGHSHDGEGG--ITRAIQMNVGLGLGLLAFSVAI
Mvan_5355|M.vanbaalenii_PYR-1       GAAHEALEA--AAHTGHSHSHGDGGG--FTRGVQMNIGMGLGVLLFSLAV
MSMEG_6089|M.smegmatis_MC2_155      SAAHQAAEH--GGHA-HVHDHGGGGGFEITRTVQSTIGLGFGVVAFGVAM
MAB_0551|M.abscessus_ATCC_1997      GEVQAALDA---AAGVHVHHEG---AELFSRFAQANAGLALGVIGFGIAM
                                       :        .     * ..   .  ::*  *   *:.:*:: *.:*:

MMAR_5097|M.marinum_M               GALFAVVFCLVYGRVGNPSASPAPRVLSIRLAALAFTVVYLVPFVKYPPN
MUL_4173|M.ulcerans_Agy99           GALFAVVFCLVYGRVGNPSASPAPRVLSIRLAALAFTVVYLVPFVKYPPN
MAV_0558|M.avium_104                GALFAVLFSVVYART----ESISPQALSLLLAAGAFGAVYLVPFVKYPPN
Mflv_1432|M.gilvum_PYR-GCK          GALFSVVYAVAYGRIG----TVSARLTSLYVAGGMLLSLYIVPSLKYPAS
Mvan_5355|M.vanbaalenii_PYR-1       GALFAVVFAVAYGRVG----NVSARLLSLYVAGGMLLSLYVVPTLKYPAS
MSMEG_6089|M.smegmatis_MC2_155      GALLAVLFCVAYGRIG----SLSARATGALLAGGMLIALWIVPALKYPPS
MAB_0551|M.abscessus_ATCC_1997      GALFSVAYVVAIGRVG----NLSPRALALSVAGGLFLVLYVVPFLKFPAN
                                    ***::* : :. .*      . :.:  .  :*.  :  :::** :*:*..

MMAR_5097|M.marinum_M               PPAVGQADTIGARTLWYLVMVVASVMLSIVAVYLVRWLSMRMDMFNAGLL
MUL_4173|M.ulcerans_Agy99           PPAVGQADTIGARTLWYLVMVVASVMLSIVAVYLVRWLSMRMDMFNAGLL
MAV_0558|M.avium_104                PPAVGQADTIGARTGWYLALVAASAALTIGVVWLARRLEARLGPWNARLL
Mflv_1432|M.gilvum_PYR-GCK          PPALSLDETIRQRTLLYLATVVLSVALLVAAVYLGRRWAARLGAWNASVA
Mvan_5355|M.vanbaalenii_PYR-1       PPALSLDETIRQRTLLYLAIVVLSAALLIGAVYLGRRWASKLGAWNAAVA
MSMEG_6089|M.smegmatis_MC2_155      PPALSLDETIQQRTLLYLLVTVLSAALLVGSVMLARKLTPKFGAWNAALI
MAB_0551|M.abscessus_ATCC_1997      PPAASAEGTIKERTGYFVLMILVAAIALAAALWVGRKLTARMDTWSATLL
                                    *** .   **  **  ::     :.      : : *    ::. :.* : 

MMAR_5097|M.marinum_M               AAGAYLVAVTVVMAILPTVAEIPQ------------GFPADVLYEFRLVS
MUL_4173|M.ulcerans_Agy99           AAGAYLVAVTVVMAILPTVAEIPQ------------GFPADVLYEFRLVS
MAV_0558|M.avium_104                SAAAYLVAIVAVAVLAPSVDETPAPLRDAAGAIVYPGFPADVLYEFRLVS
Mflv_1432|M.gilvum_PYR-GCK          AAGAYIAAVAVMMLVLPSINETPGPLRDDNGAIVYEGFPADLLYEFRLYA
Mvan_5355|M.vanbaalenii_PYR-1       AGAGYVVAIAVVMLILPSIRETPGPLVDDAGTIVYEGFPADVLYEFRLYS
MSMEG_6089|M.smegmatis_MC2_155      GAADYVVSVAVMFLLLPTISETPGPITDAEGNVLLEGFSADLLYEFRLYS
MAB_0551|M.abscessus_ATCC_1997      AAAVFVVLVGLVMAITPGFVEAPQPLLDADGKIVYPGFPAHDLYLFRLYS
                                    ... ::. :  :  : * . * *             **.*. ** *** :

MMAR_5097|M.marinum_M               LGTQLVLWASIGLVFSVLVGRGLDERADSGRVQSAAA
MUL_4173|M.ulcerans_Agy99           LGTQLVLWASIGLVFSVLVGRGLDERADSGRVQSAAA
MAV_0558|M.avium_104                LAAQLVLWAGIGLVFAAVSGRLLGARAP--RVPA---
Mflv_1432|M.gilvum_PYR-GCK          LGTQIVVYATIGLVFAAMISRLLGERKQS-VPA----
Mvan_5355|M.vanbaalenii_PYR-1       LGTQVVIYTTIGLVFAALVSRLVGDRKQS-VAP----
MSMEG_6089|M.smegmatis_MC2_155      VGTQVVMWTTIGLVFAALVSRLLDQKQQDQIPA----
MAB_0551|M.abscessus_ATCC_1997      FTTQAIMWATIGIGFATVISRKPVDTPAAV-------
                                    . :* :::: **: *:.: .*