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VWNAVVSELNGEPVADGGAANRTTLVTPLTPQQRAWLNLVRPLTIVEGFALLSVPSSFVQNEIERHLRAP ITDALSRRLGQQIQLGVRIAPPPDDVEDALIPPAEPFPDTDAALSADDGADGEPVENGEPVTDTQPGWPN YFTERPHAIDPAVAAGTSLNRRYTFDTFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLH AAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIEGKEGIQEEFFHT FNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMERLAVPDDVLE LIASSIERNIRELEGALIRVTAFASLNKTPIDKSLAEIVLRDLIADASTMQISAATIMAATAEYFDTTVE ELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTT RIRQRSKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0001 | dnaA | - | 100% (498) | chromosomal replication initiation protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0001 | dnaA | 0.0 | 87.80% (500) | chromosomal replication initiation protein |
| M. gilvum PYR-GCK | Mflv_0827 | dnaA | 0.0 | 78.64% (501) | chromosomal replication initiation protein |
| M. tuberculosis H37Rv | Rv0001 | dnaA | 0.0 | 88.20% (500) | chromosomal replication initiation protein |
| M. leprae Br4923 | MLBr_00001 | dnaA | 0.0 | 88.38% (499) | chromosomal replication initiation protein |
| M. abscessus ATCC 19977 | MAB_0001 | dnaA | 0.0 | 77.87% (497) | chromosomal replication initiation protein |
| M. marinum M | MMAR_0001 | dnaA | 0.0 | 87.17% (499) | chromosomal replication initiator protein DnaA |
| M. smegmatis MC2 155 | MSMEG_6947 | dnaA | 0.0 | 79.00% (500) | chromosomal replication initiation protein |
| M. thermoresistible (build 8) | TH_0758 | NULL | 0.0 | 80.00% (505) | CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA |
| M. ulcerans Agy99 | MUL_0001 | dnaA | 0.0 | 86.97% (499) | chromosomal replication initiation protein |
| M. vanbaalenii PYR-1 | Mvan_0001 | dnaA | 0.0 | 78.92% (498) | chromosomal replication initiation protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0001|M.avium_104 ------------------------------MWNAVVSELNGEPVADGGAA
MLBr_00001|M.leprae_Br4923 MFVPHAKKPEIYENQRDTSLADDLGLGFTTVWNAVVSELNGESNTDDEAT
Mb0001|M.bovis_AF2122/97 -------------------MTDDPGSGFTTVWNAVVSELNGDPKVDDGPS
Rv0001|M.tuberculosis_H37Rv -------------------MTDDPGSGFTTVWNAVVSELNGDPKVDDGPS
MMAR_0001|M.marinum_M -------------------MTNDPGSGFAAVWNAVVAELNGEPNTDGDAG
MUL_0001|M.ulcerans_Agy99 -------------------MTNDPGSGFAAVWNAVVAELNGEPNTDGDAG
MAB_0001|M.abscessus_ATCC_1997 -------------------MTDELNSQFTAVWNTVVAELNGDDNQ-----
Mflv_0827|M.gilvum_PYR-GCK -----------------MSLTTDPDPPFVAIWDNVVTELNG---------
Mvan_0001|M.vanbaalenii_PYR-1 -------------------MTTDPDPPFVSIWDNVVTELNG---------
MSMEG_6947|M.smegmatis_MC2_155 -------------------MTADPDPPFVAVWNSVVAELNGDVNG---DR
TH_0758|M.thermoresistible__bu ----------------------------VAVWNSVVAELNGELDSP--DS
:*: **:****
MAV_0001|M.avium_104 NRTTLVTPLTPQQRAWLNLVRPLTIVEGFALLSVPSSFVQNEIERHLRAP
MLBr_00001|M.leprae_Br4923 NDSTLVTPLTPQQRAWLNLVQPLTIIEGFALLSVPSSFVQNEIERHLRTP
Mb0001|M.bovis_AF2122/97 SDANLSAPLTPQQRAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRAP
Rv0001|M.tuberculosis_H37Rv SDANLSAPLTPQQRAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRAP
MMAR_0001|M.marinum_M TGTTLTSPLTPQQRAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRTP
MUL_0001|M.ulcerans_Agy99 TGTTLTSPLTPQQRAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRTP
MAB_0001|M.abscessus_ATCC_1997 -YLSSFPPLTPQQRAWLTLVKPLTMAEGFALLSVPSSFVQNEIERHLRGP
Mflv_0827|M.gilvum_PYR-GCK TGGTQNGSLTPQQRAWLKLVRPLVITEGFALLSVPTPFVQNEIERHLREP
Mvan_0001|M.vanbaalenii_PYR-1 AGEVGNGSLTPQQRAWLKLVKPLVITEGFALLSVPTPFVQNEIERHLREP
MSMEG_6947|M.smegmatis_MC2_155 QGDPSLPVLTPQQRAWLKLVKPLVIAEGFALLSVPTPFVQNEIERHLREP
TH_0758|M.thermoresistible__bu GGDPNRQPLTPQQRAWLKLVEPLVITEGFALLSVPTPFVQNEIERHLREP
*********.**.**.: *********:.*********** *
MAV_0001|M.avium_104 ITDALSRRLGQQIQLGVRIAPPPDDVEDALIPPAEPFPDTDAALSADDGA
MLBr_00001|M.leprae_Br4923 ITDALSRRLGQQIQLGVRIAPPSTDHID------DNSSSADVLLTDDCGT
Mb0001|M.bovis_AF2122/97 ITDALSRRLGHQIQLGVRIAPPATDEADDT---TVPPSENPATTSPDTTT
Rv0001|M.tuberculosis_H37Rv ITDALSRRLGHQIQLGVRIAPPATDEADDT---TVPPSENPATTSPDTTT
MMAR_0001|M.marinum_M ITAALSRRLGQQIQLGVRIAPPPADDDDDSVAAAVEDPGLEASPETSQEV
MUL_0001|M.ulcerans_Agy99 ITAALSRRLGQQIQLGVRIAPPPADDDDDSVAAAVEDPGLEASPETSQEV
MAB_0001|M.abscessus_ATCC_1997 IVEALSRRLGENVELGVRIAAP------------APGEDSEVAGAAPEVE
Mflv_0827|M.gilvum_PYR-GCK IVAALSRQLGQRVELGVRIADPAADDVND----GAAVTAASVPA-----D
Mvan_0001|M.vanbaalenii_PYR-1 IVAALSRQLGQRVELGVRIADPVSDESDS----GSVASPAPVAAADP--D
MSMEG_6947|M.smegmatis_MC2_155 IVTALSRKLGQRVELGVRIATPTDEPEDAPDSFADSPAPASVPAGPA--D
TH_0758|M.thermoresistible__bu IINALSRRLGQRVELGVRIATPPPQPADDPLVDTAHPQVTVEPRGGSRVD
* ****:**..::****** *
MAV_0001|M.avium_104 DGEPVENGEPVTDTQPG-WPNYFTERPHAIDP-AVAAGTSLNRRYTFDTF
MLBr_00001|M.leprae_Br4923 DTDEN-YGEPLTGEYQG-LPTYFTERPHHTES-TVTGGTSLNRRYTFETF
Mb0001|M.bovis_AF2122/97 DNDEIDDSAAARGDNQHSWPSYFTERPRNTDS-ATAGVTSLNRRYTFDTF
Rv0001|M.tuberculosis_H37Rv DNDEIDDSAAARGDNQHSWPSYFTERPHNTDS-ATAGVTSLNRRYTFDTF
MMAR_0001|M.marinum_M SDEIDDFGENAPNSRQS-WPTHFKKRSTDADTSASAGGTSLNRRYTFDTF
MUL_0001|M.ulcerans_Agy99 SDEIDDFGENAPKSRQS-WPTHFKKRSTDADTSASADGTSLNRRYTFDTF
MAB_0001|M.abscessus_ATCC_1997 LDEVDETTEALASAHES-WPSYFINRPGGADK-AETPDTSLNARYTFESF
Mflv_0827|M.gilvum_PYR-GCK TDEVDDDLAARASAEESWP-SYFN-RAKTSAE-DDSLSVNLNRRYTFETF
Mvan_0001|M.vanbaalenii_PYR-1 DDVVDDDLAARASAEESWP-SYFTNRANRAAE-DDATSVNLNRRYTFDTF
MSMEG_6947|M.smegmatis_MC2_155 ADEIDDDRDARVNAQESWP-KYFSRPEPDTSS-DDSNAVNLNRRYTFDTF
TH_0758|M.thermoresistible__bu PDDVDEDREARASAEAGWPGRYFGDRPSSSTD-GDANGATLNRRYTFETF
:* : ..** ****::*
MAV_0001|M.avium_104 VIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
MLBr_00001|M.leprae_Br4923 VIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
Mb0001|M.bovis_AF2122/97 VIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
Rv0001|M.tuberculosis_H37Rv VIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
MMAR_0001|M.marinum_M VIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
MUL_0001|M.ulcerans_Agy99 VIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
MAB_0001|M.abscessus_ATCC_1997 VIGASNRFSHAAAVAVSEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
Mflv_0827|M.gilvum_PYR-GCK VIGASNRFAHAASLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
Mvan_0001|M.vanbaalenii_PYR-1 VIGASNRFAHAASLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
MSMEG_6947|M.smegmatis_MC2_155 VIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
TH_0758|M.thermoresistible__bu VIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQR
********:***::*::*********************************
MAV_0001|M.avium_104 LFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIE
MLBr_00001|M.leprae_Br4923 LFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIE
Mb0001|M.bovis_AF2122/97 LFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIE
Rv0001|M.tuberculosis_H37Rv LFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIE
MMAR_0001|M.marinum_M LFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIE
MUL_0001|M.ulcerans_Agy99 LFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIE
MAB_0001|M.abscessus_ATCC_1997 LFPGMRVKYVSTEEFTNDFINSLRDDRRVAFKRSYRDIDVLLVDDIQFIE
Mflv_0827|M.gilvum_PYR-GCK LFPGMRVKYVSTEEFTNDFINSLRDDRRASFKRTYRDIDVLLVDDIQFIE
Mvan_0001|M.vanbaalenii_PYR-1 LFPGMRVKYVSTEEFTNDFINSLRDDRRASFKRTYRDIDVLLVDDIQFIE
MSMEG_6947|M.smegmatis_MC2_155 LFPGMRVKYVSTEEFTNDFINSLRDDRKASFKRSYRDIDILLVDDIQFIE
TH_0758|M.thermoresistible__bu LFPGMRVKYVSTEEFTNDFINSLRDDRKASFKRSYRDIDILLIDDIQFIE
***************************:.:***:***:*:**:*******
MAV_0001|M.avium_104 GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
MLBr_00001|M.leprae_Br4923 GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
Mb0001|M.bovis_AF2122/97 GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
Rv0001|M.tuberculosis_H37Rv GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
MMAR_0001|M.marinum_M GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
MUL_0001|M.ulcerans_Agy99 GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
MAB_0001|M.abscessus_ATCC_1997 GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKGLATLEDRLRTRFEWGLI
Mflv_0827|M.gilvum_PYR-GCK GKDGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
Mvan_0001|M.vanbaalenii_PYR-1 GKDGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
MSMEG_6947|M.smegmatis_MC2_155 GKEGIQEEFFHTFNTLHNSNKQIVISSDRPPKQLATLEDRLRTRFEWGLI
TH_0758|M.thermoresistible__bu GKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLI
**:***************:************* *****************
MAV_0001|M.avium_104 TDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALI
MLBr_00001|M.leprae_Br4923 TDVQPPELETRIAILRKKAQMERLAVPGDVLELIASSIERNIRELEGALI
Mb0001|M.bovis_AF2122/97 TDVQPPELETRIAILRKKAQMERLAIPDDVLELIASSIERNIRELEGALI
Rv0001|M.tuberculosis_H37Rv TDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALI
MMAR_0001|M.marinum_M TDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALI
MUL_0001|M.ulcerans_Agy99 TDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALI
MAB_0001|M.abscessus_ATCC_1997 TDVQPPELETRIAILRKKAQMDRLDVPDDVLELIASRIERNIRELEGALI
Mflv_0827|M.gilvum_PYR-GCK TDVQPPELETRIAILRKKAQMDRLDVPDDVLELIASRIERNIRELEGALI
Mvan_0001|M.vanbaalenii_PYR-1 TDVQPPELETRIAILRKKAQMDRLDVPGDVLELIASRIERNIRELEGALI
MSMEG_6947|M.smegmatis_MC2_155 TDVQPPELETRIAILRKKAQMDRLDVPDDVLELIASSIERNIRELEGALI
TH_0758|M.thermoresistible__bu TDVQPPELETRIAILRKKAQMDRLDVPDDVLELIASAIERNIRELEGALI
*********************:** :*.******** *************
MAV_0001|M.avium_104 RVTAFASLNKTPIDKSLAEIVLRDLIADASTMQISAATIMAATAEYFDTT
MLBr_00001|M.leprae_Br4923 RVTAFASLNKTAIDKALAEIVLRDLIADASTMQISAATIMTATAEYFDTT
Mb0001|M.bovis_AF2122/97 RVTAFASLNKTPIDKALAEIVLRDLIADANTMQISAATIMAATAEYFDTT
Rv0001|M.tuberculosis_H37Rv RVTAFASLNKTPIDKALAEIVLRDLIADANTMQISAATIMAATAEYFDTT
MMAR_0001|M.marinum_M RVTAFASLNKTPIDKALAEIVLRDLIADAGTMQISAATIMAATAEYFDTT
MUL_0001|M.ulcerans_Agy99 RVTAFASLNKTPIDKALAEIVLRDLIADADTMQISAATIMAATVEYFDTT
MAB_0001|M.abscessus_ATCC_1997 RVTAFASLNKSPIELSLAEIVLRDLIPDANAIQISAATIMAVTAEYFDTT
Mflv_0827|M.gilvum_PYR-GCK RVTAFASLNKTSIDKSLAEIVLRDLISDPGTMQISTAAIMAATAEYFETS
Mvan_0001|M.vanbaalenii_PYR-1 RVTAFASLNKTPIDKSLAEIVLRDLISDSSTMQISTAAIMAATAEYFETS
MSMEG_6947|M.smegmatis_MC2_155 RVTAFASLNKTRIDRSLAEVVLRDLIADATTMQISTAAIMAVTAEYFETT
TH_0758|M.thermoresistible__bu RVTAFASLNKTPIDRSLAEIVLRDLISDASTMQISAAAIMAATAEYFGTT
**********: *: :***:******.*. ::***:*:**:.*.*** *:
MAV_0001|M.avium_104 VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQ
MLBr_00001|M.leprae_Br4923 IEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQ
Mb0001|M.bovis_AF2122/97 VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQ
Rv0001|M.tuberculosis_H37Rv VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQ
MMAR_0001|M.marinum_M VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQ
MUL_0001|M.ulcerans_Agy99 VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQ
MAB_0001|M.abscessus_ATCC_1997 VEELRGPGKTRALAQARQIAMYLCRELTDLSLPKIGQTFGRDHTTVMYAD
Mflv_0827|M.gilvum_PYR-GCK VDELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAE
Mvan_0001|M.vanbaalenii_PYR-1 VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAE
MSMEG_6947|M.smegmatis_MC2_155 VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAE
TH_0758|M.thermoresistible__bu VEELRGPGKTRALAQSRQIAMYLCRELTDLSLPRIGQAFDRDHTTVMYAE
::*************:*****************:***:*.*********:
MAV_0001|M.avium_104 RKILSEMAERREVFDHVKELTTRIRQRSKR
MLBr_00001|M.leprae_Br4923 RKILSEMAERREVFDHVKELTTRIRQRSKR
Mb0001|M.bovis_AF2122/97 RKILSEMAERREVFDHVKELTTRIRQRSKR
Rv0001|M.tuberculosis_H37Rv RKILSEMAERREVFDHVKELTTRIRQRSKR
MMAR_0001|M.marinum_M RKILSEMAERREVFDHVKELTTRIRQRSKR
MUL_0001|M.ulcerans_Agy99 RKILSEMAERREVFDHVKELTTRIRQRSKR
MAB_0001|M.abscessus_ATCC_1997 KKVRGEMAQRREVFDHVKELTARIRQRSRH
Mflv_0827|M.gilvum_PYR-GCK KKIRAEMAERREVFDHVKELTTRIRQRSKR
Mvan_0001|M.vanbaalenii_PYR-1 KKIRAEMAERREVFDHVKELTTRIRQRAKR
MSMEG_6947|M.smegmatis_MC2_155 KKIRGEMAERREVFDHVKELTTRIRQRAKR
TH_0758|M.thermoresistible__bu KKIRAEMAERREVFDHVKELTTRIRQRAKR
:*: .***:************:*****:::