For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SKDSQDGPAEPSLWGATGNGVGPWELERGLPLPEDPRYDPELLRDGDARNVVDAYRYWRREAIVADIDRR RHRLHIAIENFENDANIGTVVRTANAFAVHTVHIVGRRRWNRRGAMVTDRYQHLMHHDSTDELLDYAKRA GLTVVAVDNVPGSVPLETAELPVDCLLVFGQEGPGVTDASKSGAVMTVSIAQFGSTRSINAGVAAGIAMH AWVRQHADLDGAW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4258c | - | - | 100% (224) | putative RNA methyltransferase |
| M. abscessus ATCC 19977 | MAB_0572 | - | 1e-10 | 27.98% (193) | putative tRNA/rRNA methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0387c | - | 5e-84 | 80.77% (182) | RNA methyltransferase |
| M. gilvum PYR-GCK | Mflv_0242 | - | 1e-91 | 73.61% (216) | tRNA/rRNA methyltransferase (SpoU) |
| M. tuberculosis H37Rv | Rv0380c | - | 5e-84 | 80.77% (182) | RNA methyltransferase |
| M. leprae Br4923 | MLBr_02485 | - | 2e-82 | 78.02% (182) | putative RNA methyltransferase |
| M. marinum M | MMAR_0651 | - | 8e-96 | 77.73% (220) | RNA methyltransferase |
| M. avium 104 | MAV_4788 | - | 4e-96 | 76.82% (220) | spou rRNA methylase family protein |
| M. smegmatis MC2 155 | MSMEG_0739 | - | 6e-91 | 76.06% (213) | spou rRNA methylase family protein |
| M. thermoresistible (build 8) | TH_0180 | - | 7e-93 | 78.82% (203) | POSSIBLE RNA METHYLTRANSFERASE (RNA METHYLASE) |
| M. ulcerans Agy99 | MUL_0121 | - | 8e-95 | 76.82% (220) | RNA methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0663 | - | 5e-95 | 78.40% (213) | tRNA/rRNA methyltransferase (SpoU) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0387c|M.bovis_AF2122/97 -----------------------------------------MLLRDGDAR
Rv0380c|M.tuberculosis_H37Rv -----------------------------------------MLLRDGDAR
MMAR_0651|M.marinum_M ------MSEPGPTEWGASAAGVGPWP----GEHPDDPRYDPDLLRDGDAR
MUL_0121|M.ulcerans_Agy99 --MDVAMSEPGPTEWGASAAGVGPWP----GEHPDDPRYDPDLLRDGDAR
MAV_4788|M.avium_104 ------MSEPGPTEWGTPAAGVGPWR----GELPDDPRYDPILLRDGDTR
MLBr_02485|M.leprae_Br4923 ------------------------------------------MLRDGDTR
Mflv_0242|M.gilvum_PYR-GCK -----MAEPPGPTEWGGDGHGVGPWS----GPPPDDPRYDPALLRDGDSR
Mvan_0663|M.vanbaalenii_PYR-1 -----MTDLPGPTEWGG-GHGVGPWQ----GPPPDDPRLDPELLRAGDTR
MSMEG_0739|M.smegmatis_MC2_155 -----MAEAVGPTEWGD-SPGVGPWE----GPWPDDPRYDPDLLRDGDYR
TH_0180|M.thermoresistible__bu ---------------------VGPWDESRLGPVPDDPRYDPELLRDGDTR
MAB_4258c|M.abscessus_ATCC_199 MSKDSQDGPAEPSLWGATGNGVGPWELERGLPLPEDPRYDPELLRDGDAR
:** ** *
Mb0387c|M.bovis_AF2122/97 NVVDAYRYWTREAIIADIDTRRHPLHVAIENFGHDANIGSVVRTANAFAV
Rv0380c|M.tuberculosis_H37Rv NVVDAYRYWTREAIIADIDTRRHPLHVAIENFGHDANIGSVVRTANAFAV
MMAR_0651|M.marinum_M NVVDAYRYWTREAIVADIDKRRHPLHIAIENFGHDANIGSVVRTANAFAV
MUL_0121|M.ulcerans_Agy99 NVVDAYRYWTREAIVADIDKRRHPLHIAIENFGHDANIGSVVRTANAFAV
MAV_4788|M.avium_104 NVVDAYRYWTREAIIADIDRRRHPLHVAIENFGHDANIGSVVRTANAFAV
MLBr_02485|M.leprae_Br4923 NVVDAYRYWTREAIIVDIDRRRHPFHVAIENFGHDANIGSVVRTANAFAV
Mflv_0242|M.gilvum_PYR-GCK NVVDAYRYWTREAIIADIDTRRHPLHVAIENFGNDANIGGVVRTANAFAV
Mvan_0663|M.vanbaalenii_PYR-1 NVVDAYRYWTRDAIIADIDARRHPLHIAIENFGNDANIGSVVRTANAFAV
MSMEG_0739|M.smegmatis_MC2_155 NVVDAYRYWTRPAIVADIDTRRHPLHIAIENFGSDANIGTVVRTANAFAV
TH_0180|M.thermoresistible__bu NVVDAYRYWTREAIIADIDTRRHPLHIAIENFGNDANIGSVVRTANAFAV
MAB_4258c|M.abscessus_ATCC_199 NVVDAYRYWRREAIVADIDRRRHRLHIAIENFENDANIGTVVRTANAFAV
********* * **:.*** *** :*:***** ***** **********
Mb0387c|M.bovis_AF2122/97 HTVHIVGRRRWNRRGAMVTDRYQRLCHHDSTTGLLEFAAGAGLTVVAVDN
Rv0380c|M.tuberculosis_H37Rv HTVHIVGRRRWNRRGAMVTDRYQRLCHHDSTTGLLEFAAGAGLTVVAVDN
MMAR_0651|M.marinum_M DTVHIVGRRRWNRRGAMVTDRYQRLRHHDSTAELLEFAVGAGLTVVAVDN
MUL_0121|M.ulcerans_Agy99 DTVHIVGRRRWNRRGAMVTDRYQRLRHHDSIAELLEFAVGAGLTVVAVDN
MAV_4788|M.avium_104 HTVHIVGRRRWNRRGAMVTDRYQRLCHHDSTAELLDFAATAGLTVVAVDN
MLBr_02485|M.leprae_Br4923 DTMHIVGRRRWNRRGAMVTDRYQRLCHHDSTASMLDFAAGAGLTVVAVDN
Mflv_0242|M.gilvum_PYR-GCK DTVHIVGRRRWNRRGAMVTDRYQRLCHHDTTAGLLGFAAEAGLTVVAVDN
Mvan_0663|M.vanbaalenii_PYR-1 HTVHIVGRRRWNRRGAMVTDRYQRLCHHDTTAELLDFATRAGLTVVAVDN
MSMEG_0739|M.smegmatis_MC2_155 DTVHIVGRRRWNRRGAMVTDRYQRLRHHDTTADLLDFADDAGLVVVAVDN
TH_0180|M.thermoresistible__bu HTVHIVGRRRWNRRGAMVTDRYQRLRHHDTTAALLSFAAEHDLTVVAVDN
MAB_4258c|M.abscessus_ATCC_199 HTVHIVGRRRWNRRGAMVTDRYQHLMHHDSTDELLDYAKRAGLTVVAVDN
.*:********************:* ***: :* :* .*.******
Mb0387c|M.bovis_AF2122/97 VPGAARLEQTALPRECLLLFGQEGPGITDDARAGAAVTVSIAQFGSTRSI
Rv0380c|M.tuberculosis_H37Rv VPGAARLEQTALPRECLLLFGQEGPGITDDARAGAAVTVSIAQFGSTRSI
MMAR_0651|M.marinum_M VPGAARLEETTLPRDCLLVFGQEGPGITDDTRVGAVVTVSIAQFGSTRSI
MUL_0121|M.ulcerans_Agy99 VPGAARLEETTLPRDCLLVFGREGPGITDDTRVGAVVTVSIAQFGSTRSI
MAV_4788|M.avium_104 VPGAARLEETTLPRECLLVFGQEGPGITDDTRTGATLTVSIAQFGSTRSI
MLBr_02485|M.leprae_Br4923 IPGAARLEQTTLPRQCLLVFGQEGPGITDEARTGAAMIVSIAQFGSTRSI
Mflv_0242|M.gilvum_PYR-GCK VPGAVRVEEVSLPRECLLIFGAEGPGITEDAKTGAALAVSIAQFGSTRSI
Mvan_0663|M.vanbaalenii_PYR-1 VPGASRIEEASLPRDCLLIFGQEGPGITDDAKAGAPLTVSIAQFGSTRSI
MSMEG_0739|M.smegmatis_MC2_155 VPGSVRLEETELPRNCLLIFGQEGPGITPEAQAGAAVTVSIAQFGSTRSI
TH_0180|M.thermoresistible__bu IPGAVRLEHTELPRHCLMIFGQEGPGITEDAKAGAAMTVSIAQFGSTRSI
MAB_4258c|M.abscessus_ATCC_199 VPGSVPLETAELPVDCLLVFGQEGPGVTDASKSGAVMTVSIAQFGSTRSI
:**: :* . ** .**::** ****:* :: ** : ************
Mb0387c|M.bovis_AF2122/97 NAGVAAGIAMHAWIRQHADLGRAW
Rv0380c|M.tuberculosis_H37Rv NAGVAAGIAMHAWIRQHADLGRAW
MMAR_0651|M.marinum_M NAGVAAGIAMHAWIRQHGDLSHAW
MUL_0121|M.ulcerans_Agy99 NAGVAAGIAMHAWIRQHGDLSHAW
MAV_4788|M.avium_104 NAGVAAGIAMHAWIQQHADLSRAW
MLBr_02485|M.leprae_Br4923 NAGVAAGIAMHAWIRQHADMSRAW
Mflv_0242|M.gilvum_PYR-GCK NASVAAGIVMHAWIRQHADLSRAW
Mvan_0663|M.vanbaalenii_PYR-1 NAGVAAGIAMHAWIRQHADLGRAW
MSMEG_0739|M.smegmatis_MC2_155 NAGVAAGIAMHAWITRHADMSKAW
TH_0180|M.thermoresistible__bu NAAVAAGIAMHTWVRQHADLDRAW
MAB_4258c|M.abscessus_ATCC_199 NAGVAAGIAMHAWVRQHADLDGAW
**.*****.**:*: :*.*:. **