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FAFTTPTDVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLSLRHTIAAIHRA IEDPRVAGLIARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPSTLAYYLASAFGEVWMQPSGTVG LIGFAAKGTFLRGALDKAGVEAQFLTRGQYKSAANLFTEDGYTDAQREADGRLLESLSEQVRDSVAVSRK LDPAEVDALADRAPLRRTDAVAGGLVDRIGYRDEAYARIGELIGLQDDRDPPLLYLARYARATKPQVPSL SSLPGRPSRPAIGVVTLAGPIVSGRSGPRLFPPGPASGGDVIAEALRDAVADDSVAAIVLRVDSPGGSVN GSETIWREVVRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVTGSIGVLTGKFITKGLKEKLGV GSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDAVKAVAQGRIWSGKDALE HGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSSQPAAAAVTDAVLGRVAQLAVE TVQRAQRTLGSAQAMMLGDYRF*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3789c | - | - | 100% (583) | protease IV SppA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0745 | sppA | 0.0 | 62.07% (588) | protease IV SppA |
M. gilvum PYR-GCK | Mflv_5026 | - | 0.0 | 61.36% (590) | signal peptide peptidase SppA, 67K type |
M. tuberculosis H37Rv | Rv0724 | sppA | 0.0 | 62.07% (588) | protease IV SppA |
M. leprae Br4923 | MLBr_01839 | sppA | 0.0 | 58.54% (603) | protease IV, signal peptide peptidase |
M. marinum M | MMAR_1056 | ssp | 0.0 | 61.71% (585) | protease IV, Ssp |
M. avium 104 | MAV_4443 | sppA | 0.0 | 60.97% (579) | signal peptide peptidase SppA, 67K type |
M. smegmatis MC2 155 | MSMEG_1476 | sppA | 0.0 | 60.72% (583) | signal peptide peptidase SppA, 67K type |
M. thermoresistible (build 8) | TH_0303 | sppA | 2e-97 | 65.00% (280) | POSSIBLE PROTEASE IV SPPA (ENDOPEPTIDASE IV) (SIGNAL PEPTIDE |
M. ulcerans Agy99 | MUL_0815 | ssp | 0.0 | 60.34% (585) | protease IV, Ssp |
M. vanbaalenii PYR-1 | Mvan_1343 | - | 0.0 | 62.76% (588) | signal peptide peptidase SppA, 67K type |
CLUSTAL 2.0.9 multiple sequence alignment Mb0745|M.bovis_AF2122/97 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVV-EDLRALVGRVDTARH Rv0724|M.tuberculosis_H37Rv MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVV-EDLRALVGRVDTARH MLBr_01839|M.leprae_Br4923 -----------------------MSAFLPPFPGI-DDVRALANRVNTARH MMAR_1056|M.marinum_M --------------------MFALLPFLPSLSSVGDDVRALAERVDTARH MUL_0815|M.ulcerans_Agy99 --------------------MFAFLPFLPSLSSVGDDVHALAERVDTARH MAV_4443|M.avium_104 --------------------MFAVLSSIPGLSKGADEIRALAGRVDTARH MAB_3789c|M.abscessus_ATCC_199 -----------------------MFAFTTP-----TDVHDLLAKVDTARH Mflv_5026|M.gilvum_PYR-GCK -----------------------MLALLSGVPGF-DDVRHFARKLDTARH Mvan_1343|M.vanbaalenii_PYR-1 -----------------------MFSALSGVPGF-DDVREFARKVDTARH MSMEG_1476|M.smegmatis_MC2_155 -----------------------MFGFLPGIPGQ-DDLRALVRRVDTARH TH_0303|M.thermoresistible__bu -----------------------MLAFLPGVPGA-DDLRALARKVDTARH . . ::: : :::**** Mb0745|M.bovis_AF2122/97 HGVPNGCVLEFNLRSVPPETTGFDPL-TVLT--GGGRPMALRDAVAAIHR Rv0724|M.tuberculosis_H37Rv HGVPNGCVLEFNLRSVPPETTGFDPL-TVLT--GGGRPMALRDAVAAIHR MLBr_01839|M.leprae_Br4923 HGIPNGCVLEVNLRSLPPETTSFDPF-TIIT--RGGRPMALREAVAAIHR MMAR_1056|M.marinum_M HGVPNGCILEFNLRTMPAESNGFDPL-LIIS--GGGRPMALRDAVAALHR MUL_0815|M.ulcerans_Agy99 HGVPNGCILEFNLRTMPAESNGFDPF-LIIS--GGGRPMALRDAVAALHR MAV_4443|M.avium_104 HGVPNGCVLELDLRSMPPETSGFDPL-ALVT--GGSRSASLRDTVDAIHR MAB_3789c|M.abscessus_ATCC_199 RGVPRDCILELDLLEVPPESVHLDPLGLVLS--GGSRPLSLRHTIAAIHR Mflv_5026|M.gilvum_PYR-GCK QGVPDGCILELDLQSAPPESAGFDPVALLS---GAGRPLLLREAVSALHR Mvan_1343|M.vanbaalenii_PYR-1 QGVPDGCILELDLQSAPPESAGFDPIAVISGVIGPGRPLLLREAVAAIHR MSMEG_1476|M.smegmatis_MC2_155 NGVPDGCVLELDLMSIPPETTGFDPLAMIAG---GGRPLVLRQAVAAIHR TH_0303|M.thermoresistible__bu RGVPDGCVLELDLTSIPPESGGFDPLTVLTG---RGRPMLLRDAVAAIHR .*:* .*:**.:* *.*: :**. : .*. **.:: *:** Mb0745|M.bovis_AF2122/97 AAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETYPGT Rv0724|M.tuberculosis_H37Rv AAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETYPGT MLBr_01839|M.leprae_Br4923 AAADPRVAGMIARVQLGASPPAAVQELREAVATFSAVKPSLAWAETYPGT MMAR_1056|M.marinum_M GAEDPRVAGLIARVQLPPAPIGAVQELREAIAAFSAVKPSVAWAETYPGT MUL_0815|M.ulcerans_Agy99 GAEDPRVGGLIARVQLPPAPIGAVQALREAIAAFSAVKPSVAWAETYPGT MAV_4443|M.avium_104 AAEDPRVAGLIARVQLAPSPSAAVQELREAIVAFTAAKPSLAWAETYPGT MAB_3789c|M.abscessus_ATCC_199 AIEDPRVAGLIARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPST Mflv_5026|M.gilvum_PYR-GCK AAEDPRVAGLIARVQIDAAAPGAVQELREAIVAFTAKKPSLAWAETYPGT Mvan_1343|M.vanbaalenii_PYR-1 AAEDPRVAGLIARVQIDAAPPGPVQELRDAIVAFTGKKPSLAWAETYPGT MSMEG_1476|M.smegmatis_MC2_155 AAEDDRVAGLIARVQLPAAAPGPVQELRDAIVAFGERKPTVAWAETYPGT TH_0303|M.thermoresistible__bu AAEDDRVAGLIARVQFPAASPGPVQELRAALDAFGAAKPSLAWAETYPGT . * **.*:*****: .:. ..** ** *: :* **::**:****.* Mb0745|M.bovis_AF2122/97 LSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGE Rv0724|M.tuberculosis_H37Rv LSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGE MLBr_01839|M.leprae_Br4923 LSYYLASAFGEVWMQPSGSVGLVGFASNATFLRDVLAKVGIEAQFVARGE MMAR_1056|M.marinum_M LSYYLATAFREIWMQPSGEAGLIGFASNAMFLRDALDKVGIEAQFVARGE MUL_0815|M.ulcerans_Agy99 LSYYLATAFREIWMQPSGEAGLIGFASNAMFLCDALDKVGIEAQFVARGE MAV_4443|M.avium_104 LSYYLASAFGEIWMQPGGSVGLIGFASNATFLRDALDKAGIEAQFVARGE MAB_3789c|M.abscessus_ATCC_199 LAYYLASAFGEVWMQPSGTVGLIGFAAKGTFLRGALDKAGVEAQFLTRGQ Mflv_5026|M.gilvum_PYR-GCK LSYYLASAFGEVWMQPSGTLGLVGFATNALFLRDALDKLGVEAQFIAKGE Mvan_1343|M.vanbaalenii_PYR-1 LSYYLASAFGEVWMQPSGTVGLVGFATSALFLRDALDKLGVQAQFVTRGE MSMEG_1476|M.smegmatis_MC2_155 MSYYLASAFREIWMQPAGSVGLIGFATNATFLRDALDKAGIEAQFIARGE TH_0303|M.thermoresistible__bu LSYYLASVFREVWMQPSGTVGLVGFATRALFLRDALTKAGIEAQFIARGE ::****:.* *:****.* **:***: . ** ..* * *::***:::*: Mb0745|M.bovis_AF2122/97 YKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDEL Rv0724|M.tuberculosis_H37Rv YKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDEL MLBr_01839|M.leprae_Br4923 YKSAANLFTEGGFTDAHREAVSRMLESLQGQVWQGIAESRRIDPAALNPL MMAR_1056|M.marinum_M YKSAADLFTEDGYTDANREAVTRMLESLQDQVWQAVAQSRQIDAGVLDEL MUL_0815|M.ulcerans_Agy99 YKSAADLFTEDGYTDANREAVTRMLESLQDQAWHAVAQSRQIDAGVLDEL MAV_4443|M.avium_104 YKSAVNRFTEHGFTEAHREAVTRMLDSVQEQVWQAVAESRKLDTDALDAL MAB_3789c|M.abscessus_ATCC_199 YKSAANLFTEDGYTDAQREADGRLLESLSEQVRDSVAVSRKLDPAEVDAL Mflv_5026|M.gilvum_PYR-GCK YKSAPNLFTEDRYTEPHREADTALVNGLRTQVWDAVAASRGIDVATLDAL Mvan_1343|M.vanbaalenii_PYR-1 YKSAANLFTQDSYTDAHREADTALVNGLRTQVWDAVAASRGIDRAALDAL MSMEG_1476|M.smegmatis_MC2_155 YKSAANVFTEGSYTEPHREADARLIESLQEQVWQGIAQSRGLDPDTINTL TH_0303|M.thermoresistible__bu YKSAANLFTEDSYTEPHREADSRLIESLHEQVIAAVAEARHLEPDAVNAL **** : **: :*:.:*** :::.: *. .:* :* : :: * Mb0745|M.bovis_AF2122/97 ADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS--GSQT Rv0724|M.tuberculosis_H37Rv ADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS--GSQT MLBr_01839|M.leprae_Br4923 ADRAPLLRDDAVASGLVDRIGFRDEAYARIAELVGAESITPNSSEPQART MMAR_1056|M.marinum_M ADKAPLLRDEALSSGLIDRIGFRDEAYARIAELAGVEGVSPESI------ MUL_0815|M.ulcerans_Agy99 ADKAPLLRDEALSSGLIDRIGFRDEAYARIAELARVEGVSPESI------ MAV_4443|M.avium_104 ADRAPLLRQDALDSGLVDRIGFRDQAYDRIAELVGVQDVSPDTE------ MAB_3789c|M.abscessus_ATCC_199 ADRAPLRRTDAVAGGLVDRIGYRDEAYARIGELIGLQDDRD--------- Mflv_5026|M.gilvum_PYR-GCK ADRAPLLRDDAVTAGLIDRVGFRDEAYARIADMAGADGVSPETGSGGIDP Mvan_1343|M.vanbaalenii_PYR-1 ADRAPLLRDDAVTAGLVDRIGFRDEAYARIAEMSGAEGVSPETG----DP MSMEG_1476|M.smegmatis_MC2_155 ADQAPLLREAAVTAGLVDRIGFRDEAYKRIGELAGGPENTDADH------ TH_0303|M.thermoresistible__bu ADKAPLLRDEAVTGGLIDRIGFRDEAYARIAELTGAPGISPETG---DAD **:*** * *: **:**:*:**:** *:.:: Mb0745|M.bovis_AF2122/97 SPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNG Rv0724|M.tuberculosis_H37Rv SPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNG MLBr_01839|M.leprae_Br4923 EANDGLPRLYLSRYASAGRSRLMPPMPLIPGRRSKPTVVVVTLEGPIVNG MMAR_1056|M.marinum_M DTADKLPRMHLARYAGTARPRLAPPVPSIPGRRGKPTIAVVSVEGPIVNG MUL_0815|M.ulcerans_Agy99 DIADKLPRMHLARYAGTARPRLAPPVPSIPGRRGKPTIAVVSVEGPIVNG MAV_4443|M.avium_104 -----PPRLYVSRYAGAARSRLSPPVPSLPGRRRPPTVAVINVDGTLVDG MAB_3789c|M.abscessus_ATCC_199 -----PPLLYLARYARATKP-QVPSLSSLPGRPSRPAIGVVTLAGPIVSG Mflv_5026|M.gilvum_PYR-GCK DGDDAPPRLYLTRYARAKRP-------TVPGLPNRRRIAVVTVHGPIVSG Mvan_1343|M.vanbaalenii_PYR-1 DGEDAPPRLFLARYARTKRP-------SVPGLRRHPKIAVVTVAGPIVSG MSMEG_1476|M.smegmatis_MC2_155 --DDAPPRLFLSRYAKATAPKPAPPLPSLPGRKSKPTIAVVTLHGAIVSG TH_0303|M.thermoresistible__bu TDPDAPPRLYLSRYAKATAP------------------------------ * :.::*** : . Mb0745|M.bovis_AF2122/97 RGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASE Rv0724|M.tuberculosis_H37Rv RGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASE MLBr_01839|M.leprae_Br4923 RGGPQFLPFGISTGGGDTIAAALREVAADDSVSAIVLRVNSPGGSVTASE MMAR_1056|M.marinum_M RGGPQGLPLGPSSAGGDTIASALREVAADDEVSAIVLRVDSPGGSVTASE MUL_0815|M.ulcerans_Agy99 RGGPQGLPLGPSSAGGDTIASALGETAADDEVSAIVLRVDSPGGSVTASE MAV_4443|M.avium_104 RGGPHFLPFGAATVGSDTIAPALREAAADDAVSAIVLRVNSPGGSVTASE MAB_3789c|M.abscessus_ATCC_199 RSGPRLFPPGPAS-GGDVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSE Mflv_5026|M.gilvum_PYR-GCK RGGRQMSPRGGSNAGGDTIAAALREAAADDDVAAIVVRVDSPGGSVTASE Mvan_1343|M.vanbaalenii_PYR-1 RGGRQMSPMGGSSSGADTIAAALRRAAADDDIAAIVLRVDSPGGSVTGSE MSMEG_1476|M.smegmatis_MC2_155 RGGPQPLPFGRSSAGGDTIAAALREAAANDDVAAVVLRVDSPGGSVTGSE TH_0303|M.thermoresistible__bu RSGPSX-----------------DQQRRQRHHPARIGHVERGAGVDVAHD *.* : .* : :*: .* . : Mb0745|M.bovis_AF2122/97 TIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIG Rv0724|M.tuberculosis_H37Rv TIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIG MLBr_01839|M.leprae_Br4923 TIWREVKRARDRGKPVVVSMGAVAASGGYYVSVGADEIVANPGTITGSIG MMAR_1056|M.marinum_M TIWREVQRARDRGKPVVASMGSIAASGGYYVSMGADAIVANPGTITGSIG MUL_0815|M.ulcerans_Agy99 TIWREVQRARDRGKSVVASMGSIAASGGYYVSMGADAIVANPGTITGSIG MAV_4443|M.avium_104 TLWREVKRARERGKPVVASMGAVAASGGYYVSVAADAIVANPATITGSIG MAB_3789c|M.abscessus_ATCC_199 TIWREVVRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVTGSIG Mflv_5026|M.gilvum_PYR-GCK TIWREVVRARESGTPVVASMGSVAASGGYYVSMAADAIVANPATITGSIG Mvan_1343|M.vanbaalenii_PYR-1 TIWREVVRTRERGKPVVASMGAVAASGGYYVSMAADAIVANPGTITGSIG MSMEG_1476|M.smegmatis_MC2_155 TVWREVVRTRDAGKPVVASMGAVAASGGYYVSMAADEIVANAGTITGSIG TH_0303|M.thermoresistible__bu RRHHDEVEDRQ--QHQVLCHGQADRPG---VVALLDLVFVEHG--RRCVT :: . *: * . * .* * * :..: . .: Mb0745|M.bovis_AF2122/97 VITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEAD Rv0724|M.tuberculosis_H37Rv VITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEAD MLBr_01839|M.leprae_Br4923 VITGKLVIRDLKGRLGVGSDTVRTNANADAWSANVPFTPEQHTHREAEAD MMAR_1056|M.marinum_M VITGKLVVRDLKDRLGVGSETLRTNANADAWSIDAPFTDEQRARREAEAD MUL_0815|M.ulcerans_Agy99 VITGKLVVRDLKDRLGVGSETLRTNANADAWSIDAPFTDEQRARREAEAD MAV_4443|M.avium_104 VITGKLVIRDLLGRLGVGSDTVRTNANADAWSIDAPFTPEQRAHREAEAD MAB_3789c|M.abscessus_ATCC_199 VLTGKFITKGLKEKLGVGSDSLRTNANADAWSSNEPFTDEQRDLVEAEID Mflv_5026|M.gilvum_PYR-GCK VVTGKLVARDLKERLGVGSDSVRTNANADAWSINAPFTEEQHAQVAAEAD Mvan_1343|M.vanbaalenii_PYR-1 VLTGKLVARELKDRLGVGSDTVRTNANADAWSINAPFTDEQQAHVEAEAD MSMEG_1476|M.smegmatis_MC2_155 VLTGKFVSRELKDKLGVGSDAVRTNANADAWSTNAPFTDEQHARVEAEAD TH_0303|M.thermoresistible__bu LAAG----HDLQHQK------RREEDQGGRQPDQGRLTETQGAHHTDDG- : :* : * : * : :.. . : :* * : Mb0745|M.bovis_AF2122/97 LFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTA Rv0724|M.tuberculosis_H37Rv LFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTA MLBr_01839|M.leprae_Br4923 LCYADFLERVAEGRGMTTDAVDDVARGRIWTGADALERGLVDELGGLVTA MMAR_1056|M.marinum_M MFYTDFVERVARGRNLRTEDVDAVARGRVWTGADALERGLVDELGGFRTA MUL_0815|M.ulcerans_Agy99 MFYTDFAERVARGRNLRTEDVDAVARGRVWTGADALERGLVDELGGFRTA MAV_4443|M.avium_104 LVYTDFVSRVAEGRNLTTDAVERVARGRVWTGADAHERGLVDELGGFRIA MAB_3789c|M.abscessus_ATCC_199 MHYEDFVQRVADGRNLTVDAVKAVAQGRIWSGKDALEHGLVDELGGFREA Mflv_5026|M.gilvum_PYR-GCK LFYDDFVARVAEGRGLSVDAVEKVARGRVWTGADALDRGLVDELGGLRTA Mvan_1343|M.vanbaalenii_PYR-1 LFYRDFVQRVAEGRHLSVEAVEQVARGRVWTGADALERGLVDELGGLRTA MSMEG_1476|M.smegmatis_MC2_155 LLYRDFVERAAEGRKLPIEEMESLARGRVWTGSDAKERGLVDHVGGLRAA TH_0303|M.thermoresistible__bu --HRRQRQRQDDD-EHPAPALGAPPRKGVEIGALILE-----EPPGAVVL : * . : .: : * : . * Mb0745|M.bovis_AF2122/97 VRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGAL Rv0724|M.tuberculosis_H37Rv VRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGAL MLBr_01839|M.leprae_Br4923 VRRAKVLAGLDADVDVRIVSYPGSSLLDMVRPRASSQPGAASLPDAVATL MMAR_1056|M.marinum_M VRRAKVLAGLDEDTEVRLVGYPGSSLLDLLWPRGSSRPVAASVPEAVGTL MUL_0815|M.ulcerans_Agy99 VPRAKVLAGLDEDTEVRPVGYPGSLLLDLLWPRGSSRPVAASVPEAVGAL MAV_4443|M.avium_104 VRRAKILAGLDEDADVRIVTYPSGSLLDVLRPRASSQPAAVSLPDALGAL MAB_3789c|M.abscessus_ATCC_199 VAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSSQPAAAAVTDAVLGR Mflv_5026|M.gilvum_PYR-GCK VTRAKALAGIDEDTKVELQMLPGASLRDVLRPKPSSQPAAASLPELLGAL Mvan_1343|M.vanbaalenii_PYR-1 IRRAKVLAGIDEDTRVEVENLPSSSLLDVLRPKPSSLPAAASLQEVFGAL MSMEG_1476|M.smegmatis_MC2_155 VTRAKVLAGFDEDADARVVAYPGSSWLDMLRPKPSSQPAAASLPEALAAL TH_0303|M.thermoresistible__bu VTVEQGGAGR-SGGSVR----HGKSLRAVVRPFGRARSTTG--------- : : *. . .. . :: : . : Mb0745|M.bovis_AF2122/97 LARSIVGIVEQVEQTLSGASVLWLGESRL Rv0724|M.tuberculosis_H37Rv LARSIVGIVEQVEQTLSGASVLWLGESRL MLBr_01839|M.leprae_Br4923 LGRSVAGILEQVEQALSGVRVLWLGEYRF MMAR_1056|M.marinum_M VVRSVAGAVGQVEQTLTGANVLWLGRSRF MUL_0815|M.ulcerans_Agy99 VVRSVAGAVGQVEQTLTGANVLWLGRSRF MAV_4443|M.avium_104 TVKILGAILDNVERSCSGASALWLGPSRL MAB_3789c|M.abscessus_ATCC_199 VAQLAVETVQRAQRTLGSAQAMMLGDYRF Mflv_5026|M.gilvum_PYR-GCK AIQSVAGVVDQTQRSLSGVNALWTGNPRF Mvan_1343|M.vanbaalenii_PYR-1 AIQSVLGIADRTQRSLTGVNVLWLGETRY MSMEG_1476|M.smegmatis_MC2_155 LGKSVIGVLDQAERSMTGASALWLGEYRF TH_0303|M.thermoresistible__bu -----------------------------