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HSDTTISPQIDPFTARFGVPLPRGLREEAGDMSWASFCQTYERSGGALRLGQWSQTGGTYQATLTIGECI ESATVSACGPMAALTAMLSEHGIPMETLSFHQLRDGDQTCTFIRGTNGLGTAWAMGRAPDATTSSLKAVT ACANRLAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3424c | - | - | 100% (149) | hypothetical protein MAB_3424c |
| M. abscessus ATCC 19977 | MAB_0337c | - | 4e-06 | 36.25% (80) | 2-isopropylmalate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4316 | - | 3e-30 | 46.94% (147) | hypothetical protein Mflv_4316 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_02324 | leuA | 4e-07 | 30.10% (103) | 2-isopropylmalate synthase |
| M. marinum M | MMAR_1633 | - | 1e-34 | 48.63% (146) | hypothetical protein MMAR_1633 |
| M. avium 104 | MAV_3928 | - | 2e-39 | 55.48% (146) | hypothetical protein MAV_3928 |
| M. smegmatis MC2 155 | MSMEG_2288 | - | 3e-30 | 45.39% (152) | hypothetical protein MSMEG_2288 |
| M. thermoresistible (build 8) | TH_1634 | - | 3e-24 | 46.46% (127) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3403 | - | 4e-34 | 47.95% (146) | hypothetical protein MUL_3403 |
| M. vanbaalenii PYR-1 | Mvan_2030 | - | 7e-34 | 52.59% (135) | hypothetical protein Mvan_2030 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 MASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYR
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 PFAKEVEPIRLVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRR
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 MFDLLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIPDDVTIQVLTQCR
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 PELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKAIATDGAR
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 KCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDE
MSMEG_2288|M.smegmatis_MC2_155 --------------------------------------------------
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2030|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1633|M.marinum_M --------------------------------------------------
MUL_3403|M.ulcerans_Agy99 --------------------------------------------------
MAV_3928|M.avium_104 --------------------------------------------------
MAB_3424c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02324|M.leprae_Br4923 IRRTVEYCNKLRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIDADAA
MSMEG_2288|M.smegmatis_MC2_155 ------------------------MFTAPAIRTSS--ASSSSSFASCFAA
TH_1634|M.thermoresistible__bu --------------------------------------------------
Mflv_4316|M.gilvum_PYR-GCK ---------------------MNVSSNTHPTTASS--ASASLPFAAHVDG
Mvan_2030|M.vanbaalenii_PYR-1 -----------------------------------------MTFAAVVDG
MMAR_1633|M.marinum_M ---------------MTLLTTFDLDLDPEPIDGSARKPGARAHFAGIFGV
MUL_3403|M.ulcerans_Agy99 ---------------MTLLTTFDLDLDPEPIDGSARKPGARAHFAGIFGV
MAV_3928|M.avium_104 -------------------------MTIPERNRLPHPESATAWFGDRFGV
MAB_3424c|M.abscessus_ATCC_199 ------------------------------MHSDTTISPQIDPFTARFGV
MLBr_02324|M.leprae_Br4923 DSDVDDILWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKADHGL
MSMEG_2288|M.smegmatis_MC2_155 PLPRGLR----------------AVAQEQTWDAFLARFAAIAGPVTLRQW
TH_1634|M.thermoresistible__bu ----------------------------MSPEAVLAEYAAPPGPVRLGHW
Mflv_4316|M.gilvum_PYR-GCK RTPRALR----------------ELAEIKSFDEFLAVYAPTSGPLRLGQW
Mvan_2030|M.vanbaalenii_PYR-1 LLPRALR----------------EPAETKSFDEFCDEYAPSTGPVRLGQW
MMAR_1633|M.marinum_M DLPRGLR----------------EQAATMSWDRFVATYGRTGGPVRLGHW
MUL_3403|M.ulcerans_Agy99 GLPRGLR----------------EQAATMSWDRFVATYGRTGGPVRLGHW
MAV_3928|M.avium_104 PLPRGLR----------------ERAEAMSWDAFVATYGRSGGPLRLGPW
MAB_3424c|M.abscessus_ATCC_199 PLPRGLR----------------EEAGDMSWASFCQTYERSGGALRLGQW
MLBr_02324|M.leprae_Br4923 ELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQPLERIKQ
. : .:
MSMEG_2288|M.smegmatis_MC2_155 SCVDS-RPTGQIGPR--EYQATLSIGDTVATSSVTAYGPVAALTEILHAH
TH_1634|M.thermoresistible__bu ECIDAGRPVSRMGPRPLRYQATLAVGDTTSTSTATAIGPVAALTEMLHER
Mflv_4316|M.gilvum_PYR-GCK TCVDDDRPGRRLGPQARQYQATLAVGDRIATSRAAACGPVAALTEMLHEH
Mvan_2030|M.vanbaalenii_PYR-1 ACVDG---ARRLGPQVRSYQATLALGDRTGTSRAAACGPVAALTEMLHER
MMAR_1633|M.marinum_M ECTDADRPSGRLGPQARSFRAMIAVGDRMSTSTAAAGGPMAALTAMLHDR
MUL_3403|M.ulcerans_Agy99 ECTDADRPSGRLGPQARSFRAMIAVGDQMSTSTAAAGGPMAALTAMLHDR
MAV_3928|M.avium_104 ERTDSDCAATGLGSRAGNYRAVIAVGDQIGTATAAAAGPIAALTAMLHER
MAB_3424c|M.abscessus_ATCC_199 SQTGG------------TYQATLTIGECIESATVSACGPMAALTAMLSEH
MLBr_02324|M.leprae_Br4923 RVNAAEEDGGS-----TSIAATVKINGEETEISGVGNGPLAAFIDALGHV
* : :. . **:**: *
MSMEG_2288|M.smegmatis_MC2_155 GITVETTSFHQLPTRG----QTATFIEGSNGVHREWAMGLDTDPVQSALR
TH_1634|M.thermoresistible__bu GVAVETVSFHQVPAGQ----CTATFLHGTNGVRAEWAMGWAEDPTRSALG
Mflv_4316|M.gilvum_PYR-GCK GIAIEMTAFHQVPAGD----HTATFIRGSRCGGEQWAMGWSDDSTDSALR
Mvan_2030|M.vanbaalenii_PYR-1 GVAVEMTAFHQLRAGD----HTATFIRGSNGCRTRWAMGWSDDATESALR
MMAR_1633|M.marinum_M AIMVETLKFHQVQSGP----HTATFICGTNGVRSQWAMGWSQDPTQSALR
MUL_3403|M.ulcerans_Agy99 AIMVETLKFHQVQSGP----HTAAFICGTNGVRSQWAMGWSQDPTQSALR
MAV_3928|M.avium_104 GINLEILNFHQMRSAT----ATATFIRGGNGGRAEWAMGWSPDPTRSALR
MAB_3424c|M.abscessus_ATCC_199 GIPMETLSFHQLRDGD----QTCTFIRGTNGLGTAWAMGRAPDATTSSLK
MLBr_02324|M.leprae_Br4923 GLQVAVLDYSEHAMNAGDDAQAAAYVEASVHGHTAWGVGIAPSITTASLR
.: : : : :.::: . *.:* . . ::*
MSMEG_2288|M.smegmatis_MC2_155 AVIACANRLTAH-------
TH_1634|M.thermoresistible__bu AVIACANRLLS--------
Mflv_4316|M.gilvum_PYR-GCK AVIACANRLLSA-------
Mvan_2030|M.vanbaalenii_PYR-1 AVIACANRLIADS------
MMAR_1633|M.marinum_M ALIACANRLLD--------
MUL_3403|M.ulcerans_Agy99 ALIACANRLLD--------
MAV_3928|M.avium_104 AVIACANRLFAPEWPDGSR
MAB_3424c|M.abscessus_ATCC_199 AVTACANRLAR--------
MLBr_02324|M.leprae_Br4923 AVVSAVNRAMPR-------
*: :..**