For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_3072 (-)

annotation: N-acetylglutamate synthase
coordinates: 3118571 - 3119131
length: 186

MSAEGTSGISDNPGHPAPAVTVRRARTSDVPAIKALVDVYAGRILLEKNLVTLYEAVQEFWVADLDGEIV
GCGALHVLWSDLGEVRTIAVHPRLKGAGVGHALVSRLLEVASELELKRVFVLTFEVDFFAKHGFREIDGT
PVTAEVYEEMCRSYDTGVAEFLDLSYVKPNTLGNTRMLAHLSSRPT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3072--100% (186)N-acetylglutamate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2768-1e-7078.75% (160) N-acetylglutamate synthase
M. gilvum PYR-GCKMflv_3990-1e-7684.71% (157) N-acetylglutamate synthase
M. tuberculosis H37RvRv2747-1e-7078.75% (160) N-acetylglutamate synthase
M. leprae Br4923MLBr_00978-3e-7078.12% (160) N-acetylglutamate synthase
M. marinum MMMAR_1968-3e-7078.12% (160) acetyltransferase
M. avium 104MAV_3638-1e-7175.14% (173) N-acetylglutamate synthase
M. smegmatis MC2 155MSMEG_2691-9e-7986.88% (160) N-acetylglutamate synthase
M. thermoresistible (build 8)TH_0578-1e-7885.00% (160) POSSIBLE TRANSFERASE
M. ulcerans Agy99MUL_3389-2e-7078.12% (160) N-acetylglutamate synthase
M. vanbaalenii PYR-1Mvan_2394-2e-7676.30% (173) N-acetylglutamate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2768|M.bovis_AF2122/97            --------MTERPRDCRP--VVRRARTSDVPAIKQLVDTYAGKILLEKNL
Rv2747|M.tuberculosis_H37Rv         --------MTERPRDCRP--VVRRARTSDVPAIKQLVDTYAGKILLEKNL
MAV_3638|M.avium_104                --------MTESPQRYRP--LVRRARTSDVPAIKELVDTYAGKILLEKNL
MMAR_1968|M.marinum_M               --------MTESQQDFRP--VVRRARTSDVPAIKKLVDTYAGKILLEKNL
MUL_3389|M.ulcerans_Agy99           --------MTESQQDFRP--VVRRARTSDVPAIKKLVDTYAGKILLEKNL
MLBr_00978|M.leprae_Br4923          --MSILLAVTKNSQNYLP--VVRRARTSDIPAIKQLVDTYAGKILLEKNL
MAB_3072|M.abscessus_ATCC_1997      MSAEGTSGISDNPGHPAPAVTVRRARTSDVPAIKALVDVYAGRILLEKNL
MSMEG_2691|M.smegmatis_MC2_155      ---------------------MRRARTSDVPGIKHLVDIYAGRILLEKNL
Mflv_3990|M.gilvum_PYR-GCK          --------------------MVRRARTSDVPHIKALVDIYAGRILLEKNL
Mvan_2394|M.vanbaalenii_PYR-1       --------MSADPDAATGQLLVRRARTSDVPAIKALVDIYAGKILLEKNL
TH_0578|M.thermoresistible__bu      ---------------------VRRARTSDVPAIKALVDIYAGRILLEKNL
                                                         :*******:* ** *** ***:*******

Mb2768|M.bovis_AF2122/97            VTLYEAVQEFWVAEHPDLYGKVVGCGALHVLWSDLGEIRTVAVDPAMTGH
Rv2747|M.tuberculosis_H37Rv         VTLYEAVQEFWVAEHPDLYGKVVGCGALHVLWSDLGEIRTVAVDPAMTGH
MAV_3638|M.avium_104                VTLYEAVQEFWVAELPDSPGRVVGCGALHVLWSDLGEIRTVAVNPAMTGH
MMAR_1968|M.marinum_M               VTLYEAVQEFWVAEHPEIQGNVIGCGALHVLWSDLGEVRTVAVDPAMTGH
MUL_3389|M.ulcerans_Agy99           VTLYEAVQEFWVAEHPEIQGNVIGCGALHVLWSDLGEVRTVAVDPAMTGH
MLBr_00978|M.leprae_Br4923          VTLYEAVQEFWVAEHPDIPGKVVGCGALHVLWSDLGEIRTVAVDPAMTGH
MAB_3072|M.abscessus_ATCC_1997      VTLYEAVQEFWVADL---DGEIVGCGALHVLWSDLGEVRTIAVHPRLKGA
MSMEG_2691|M.smegmatis_MC2_155      VTLYESVQEFWVAEL---DGEIVGCGALHVLWADLGEVRTVAVHPKVRGT
Mflv_3990|M.gilvum_PYR-GCK          VTLYESVQEFWVAEV---DGEVVGCGALHVLWSDLGEVRTVAVDPKVRGR
Mvan_2394|M.vanbaalenii_PYR-1       VTLYESVQEFWVAEI---DGELIGCGALHVMWSDLGEVRTVAVHPKALGR
TH_0578|M.thermoresistible__bu      VTLYESVQEFWVAER---DGELVGCGALHVMWSDLGEVRTVAVHPKVRGQ
                                    *****:*******:     *.::*******:*:****:**:**.*   * 

Mb2768|M.bovis_AF2122/97            GIGHAIVDRLLQVARDLQLQRVFVLTFETEFFARHGFTEIEGTPVTAEVF
Rv2747|M.tuberculosis_H37Rv         GIGHAIVDRLLQVARDLQLQRVFVLTFETEFFARHGFTEIEGTPVTAEVF
MAV_3638|M.avium_104                GIGHAIVDRLLQVARELELKRLFVLTFETEFFGKHGFTEIEGTPVTAEVF
MMAR_1968|M.marinum_M               GIGHAIVDRLLEVARELQLERLFVLTFETEFFTAHGFTEIEGTPVTAEVF
MUL_3389|M.ulcerans_Agy99           GIGHAIVDRLLEVARELQLERLFVLTFETEFFTAHGFTEIEGTPVTAEVF
MLBr_00978|M.leprae_Br4923          GVGGTIVNRLLEVARKLELERLFVLTFETEFFSQHGFTEIEGTPVTAEVF
MAB_3072|M.abscessus_ATCC_1997      GVGHALVSRLLEVASELELKRVFVLTFEVDFFAKHGFREIDGTPVTAEVY
MSMEG_2691|M.smegmatis_MC2_155      GVGHRLVNRLLDVARELRLERIFVLTFEVDFFAKHGFVEIDGTPVTAEVY
Mflv_3990|M.gilvum_PYR-GCK          GVGHAIVERLLTVAADLRLQRIFVLTFEVDFFARHGFQEIEGTPVTAEVY
Mvan_2394|M.vanbaalenii_PYR-1       GVGHAIVERLLSVAADLHLRRIFVLTFEVEFFGRHGFQEIEGTPVTSEVY
TH_0578|M.thermoresistible__bu      GVGHMIVERLLDVARELELERIFVLTFEVEFFARHGFREIEGTPVTAEVY
                                    *:*  :*.*** ** .*.*.*:******.:**  *** **:*****:**:

Mb2768|M.bovis_AF2122/97            DEMCRSYDIGVAEFLDLSYVKPNILGNSRMLLVL-----
Rv2747|M.tuberculosis_H37Rv         DEMCRSYDIGVAEFLDLSYVKPNILGNSRMLLVL-----
MAV_3638|M.avium_104                EEMCRSYDIGVAEFLDLSYVKPNILGNSRMLLVL-----
MMAR_1968|M.marinum_M               EEMCRSYDIGVAEFLDLSYIKPNILGNTRMLLVL-----
MUL_3389|M.ulcerans_Agy99           EEMCRSYDIGVAEFLDLSYIKPNILGNTRMLLVL-----
MLBr_00978|M.leprae_Br4923          EEMCRSYDIGVAEFLDLSYVKPNTLGNSRMLLVL-----
MAB_3072|M.abscessus_ATCC_1997      EEMCRSYDTGVAEFLDLSYVKPNTLGNTRMLAHLSSRPT
MSMEG_2691|M.smegmatis_MC2_155      EEMCRSYDTGVAEFLDLSYVKPNTLGNTRMLLTL-----
Mflv_3990|M.gilvum_PYR-GCK          EEMCRSYDTGVAEFLDLSYVKPNILGNTRMLLLL-----
Mvan_2394|M.vanbaalenii_PYR-1       EEMCRSYDTGVAEFLDLSYVKPNILGNTRMLLTL-----
TH_0578|M.thermoresistible__bu      EEMCRSYDTGVAEFLDLSYVKPNILGNTRMLLNL-----
                                    :******* **********:*** ***:***  *