For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTQIPNGSADTDRAAIRDSELTVIGRIRSASNATFLCEVQNTSGEGVHCVYKPVRGEQPLWDFPDGTLAG REVATYLISAELGWNVVPYTVFRDGPAGVGMVQQWIHEPELAEGALDLVDICLPEAIPSGYLPILRALDA DGAEIVLVHADDSLLRRMAVFDTLVNNADRKGGHILRGADGGVYGVDHGICLHAQDKLRTVLWGWAGKPV EPELLADVVRLEEVLRGEFGTVLEAHVTTEEVAALRQRAAMMLDEPVMPTPDRNRPIPWPAF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2111 | - | - | 100% (272) | putative phosphatidylinositol 3-and 4-kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2157c | - | 6e-92 | 60.46% (263) | hypothetical protein Mb2157c |
| M. gilvum PYR-GCK | Mflv_3046 | - | 3e-98 | 63.70% (270) | phosphatidylinositol 3- and 4-kinase, catalytic |
| M. tuberculosis H37Rv | Rv2133c | - | 6e-92 | 60.46% (263) | hypothetical protein Rv2133c |
| M. leprae Br4923 | MLBr_01300 | - | 6e-94 | 60.69% (262) | hypothetical protein MLBr_01300 |
| M. marinum M | MMAR_3113 | - | 5e-96 | 63.67% (267) | hypothetical protein MMAR_3113 |
| M. avium 104 | MAV_2359 | - | 1e-98 | 64.26% (277) | hypothetical protein MAV_2359 |
| M. smegmatis MC2 155 | MSMEG_4191 | - | 2e-93 | 61.28% (266) | hypothetical protein MSMEG_4191 |
| M. thermoresistible (build 8) | TH_2361 | - | 7e-96 | 63.57% (269) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2363 | - | 1e-92 | 62.60% (262) | hypothetical protein MUL_2363 |
| M. vanbaalenii PYR-1 | Mvan_3480 | - | 1e-97 | 63.16% (266) | phosphatidylinositol 3- and 4-kinase, catalytic |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3113|M.marinum_M MTPRNDER-----------EVVRDGELTVLGRIRSASNATFLCEST-LGD
MUL_2363|M.ulcerans_Agy99 ---------------------MRDGELTVLGRIRSASNATFLCEST-LDD
MLBr_01300|M.leprae_Br4923 --------------------MLRNGELTVLGRIRSASNATFLCEST-LDQ
Mb2157c|M.bovis_AF2122/97 --------------------MLADGELTVLGRIRSASNATFLCEST-LGL
Rv2133c|M.tuberculosis_H37Rv --------------------MLADGELTVLGRIRSASNATFLCEST-LGL
MAV_2359|M.avium_104 MTPRYDDR-----------EVLRDGELTVIGRIRSASNATFLCEAT-LGD
Mflv_3046|M.gilvum_PYR-GCK MTSSDSE------------KVLRLGELTVIGRIRSASNATFLCEAT-LDG
Mvan_3480|M.vanbaalenii_PYR-1 MTSCDFG------------EVLRCGELTVIGRIRSASNATFLCEAT-LGA
MSMEG_4191|M.smegmatis_MC2_155 MTSEVSAAASGKPDDIPDIEVLERGELTVIGRIRSASNATFLCESH-LGD
TH_2361|M.thermoresistible__bu --------------------VLQHGELTVIGRIRSASNATFLCEAQ-LDE
MAB_2111|M.abscessus_ATCC_1997 MTQIPNGSADTDR------AAIRDSELTVIGRIRSASNATFLCEVQNTSG
: .****:************** .
MMAR_3113|M.marinum_M NTVHCVYKPVSGEQPLWDFPDGTLAGRELSAYHVSAQLGWNIVPYTVIRD
MUL_2363|M.ulcerans_Agy99 NTVHCVYKPVSGEQPLWDFPDGTLAGRELSAYHVSAQLGWNIVPYTVIRD
MLBr_01300|M.leprae_Br4923 RSVHCVYKPVSGEQPLWDFPEGTLAGRELSAYLVSTDLGWNIVPYTVIRD
Mb2157c|M.bovis_AF2122/97 RSLHCVYKPVSGERPLWDFPDGTLAGRELSAYLVSTQLGWNLVPHTIIRD
Rv2133c|M.tuberculosis_H37Rv RSLHCVYKPVSGERPLWDFPDGTLAGRELSAYLVSTQLGWNLVPHTIIRD
MAV_2359|M.avium_104 RAVHCVYKPVAGEAPLWDFPDGTLAGRELGAYLVSTQLGWNLVPYTVIRD
Mflv_3046|M.gilvum_PYR-GCK DTEHCVYKPVRGEAPLWDFPDGTLAGRERASYLVSAALGWNVVPYTIIRD
Mvan_3480|M.vanbaalenii_PYR-1 DTWHCVYKPVRGEAPLWDFPDGTLAGREVASYLVSAAMGWNVVPYTIIRD
MSMEG_4191|M.smegmatis_MC2_155 RQVHCVYKPVAGEAPLWDFPDGTLAGRERGAYLVSAALGWNLVPHTIVRD
TH_2361|M.thermoresistible__bu QRVHCVYKPVAGEAPLWDFPDGTLAGRERGAYLVSVALGWNIVPYTIIRD
MAB_2111|M.abscessus_ATCC_1997 EGVHCVYKPVRGEQPLWDFPDGTLAGREVATYLISAELGWNVVPYTVFRD
******* ** ******:******* .:* :*. :***:**:*:.**
MMAR_3113|M.marinum_M GPAGPGMLQLWVQQPGDAVGTD----------PRPGPDLVDLFPCGKPQP
MUL_2363|M.ulcerans_Agy99 GPAGPGMLQLRVQQPGDAVGTD----------PRPGPDLVDLFPCGKPQP
MLBr_01300|M.leprae_Br4923 GPAGPGMLQLWVQQPGDVADSA----------PRSGPDMVDLFPADKLQS
Mb2157c|M.bovis_AF2122/97 GPAGIGMLQLWVQQPGDAVDSD----------PLPGPDLVDLFPAHRPRP
Rv2133c|M.tuberculosis_H37Rv GPAGIGMLQLWVQQPGDAVDSD----------PLPGPDLVDLFPAHRPRP
MAV_2359|M.avium_104 GPAGPGMLQLWVRQPGDAVGEVSEAGESGAEQPDPGPDLVDLFPVGASPP
Mflv_3046|M.gilvum_PYR-GCK GPAGPGMLQRWVDQPGDDD-------DADAD---TGPDLIDLLPAGKIPA
Mvan_3480|M.vanbaalenii_PYR-1 GPAGLGMVQRWVDQPGDDDT------DDDRDDRPAGPDLIDLVPAGRVPA
MSMEG_4191|M.smegmatis_MC2_155 GPAGPGMVQRWVDQPGDEVG------DDPYT----GPDLVDLLPAGQVPP
TH_2361|M.thermoresistible__bu GPAGAGMVQRWIDQPGDTDDPA---GSESAEQPGSGPDLVDLLPAGQVTP
MAB_2111|M.abscessus_ATCC_1997 GPAGVGMVQQWIHEPELAEG---------------ALDLVDICLPEAIPS
**** **:* : :* . *::*: .
MMAR_3113|M.marinum_M GYLPVLRAYDYSGDEVILMHADDVRLRRMAVFDVLINNADRKGGHILYGV
MUL_2363|M.ulcerans_Agy99 GYLPVLRAYDYSGDEVILMHADDVRLRRMAVFDVLINNADRKGGHILCGV
MLBr_01300|M.leprae_Br4923 GYLPVLRSYNYAGDEVILMHADDTQLRRLAVFDVLINNADRKGGHILYGL
Mb2157c|M.bovis_AF2122/97 GYLPVLRAYDYAGDEVVLMHADDIRLRRMAVFDVLINNADRKGGHILCGI
Rv2133c|M.tuberculosis_H37Rv GYLPVLRAYDYAGDEVVLMHADDIRLRRMAVFDVLINNADRKGGHILCGI
MAV_2359|M.avium_104 GYLPVLRAYDYAGDEVVLMHADDPRLRRMAVFDVLVNNADRKGGHILCGV
Mflv_3046|M.gilvum_PYR-GCK GFLPVLQAYDYAGDEVTLVHADDDRLRRIAVFDVLINNADRKGGHVLHGV
Mvan_3480|M.vanbaalenii_PYR-1 GFLPVLQAYDYAGDEVTLVHADDERLRRIAVFDVLVNNADRKGGHVLHGV
MSMEG_4191|M.smegmatis_MC2_155 GFLPILQAYDYAGDEVTLVHADDPRLFRLAVFDVLINNADRKGGHVLSGV
TH_2361|M.thermoresistible__bu GYLAVLQAYDYAGNEVVLAHADDERLHRMAVFDVLINNADRKGGHILAGV
MAB_2111|M.abscessus_ATCC_1997 GYLPILRALDADGAEIVLVHADDSLLRRMAVFDTLVNNADRKGGHILRGA
*:*.:*:: : * *: * **** * *:****.*:*********:* *
MMAR_3113|M.marinum_M DDRVYGVDHGVSMHVQDKLRTVLWGWAGKPIDDQTLQTVAGLIDDLRGKL
MUL_2363|M.ulcerans_Agy99 DDRVYGVDHGVSMHVQDKLRTVLWGWAGKPIDDQTLQKVAGLIDDLRGKL
MLBr_01300|M.leprae_Br4923 DGHVYGVDHGVSLHVEDKLRTVLWGWAGKPIDNQTLEEVAGLADALSGPL
Mb2157c|M.bovis_AF2122/97 DGQVYGVDHGLCLHVENKLRTVLWGWAGKPIDDQILQAVAGLADALGGPL
Rv2133c|M.tuberculosis_H37Rv DGQVYGVDHGLCLHVENKLRTVLWGWAGKPIDDQILQAVAGLADALGGPL
MAV_2359|M.avium_104 DGRVYGVDHGVCLHVENKLRTVLWGWAGKPVDDDSLAAVACLAEALTGPF
Mflv_3046|M.gilvum_PYR-GCK DGGVYGVDHGVTLHEEDKLRTVLWGWAGKPVDDESLSDIRDLGEKLNAGL
Mvan_3480|M.vanbaalenii_PYR-1 DGGVYGVDHGVTLHVEDKLRTVLWGWAGKPVDDETLSDVAKLGDALNADL
MSMEG_4191|M.smegmatis_MC2_155 DGGVYGVDHGVTLHVEDKLRTVLWGWAGKPIDDDTLADIAALRDGFNTGL
TH_2361|M.thermoresistible__bu DGGVYGVDHGVTLHSEDKLRTVLWGWAGKPVDDAMLSAVERLRRQLDGAL
MAB_2111|M.abscessus_ATCC_1997 DGGVYGVDHGICLHAQDKLRTVLWGWAGKPVEPELLADVVRLEEVLRGEF
*. *******: :* ::*************:: * : * : :
MMAR_3113|M.marinum_M GETLAGLITRAEVVALGRRAEMLLDNPVMPGPDRHRPIPWPAF
MUL_2363|M.ulcerans_Agy99 GETLAGLITHAEIVALGRRAEMLLENPVMPGPDRHRPIPWPAF
MLBr_01300|M.leprae_Br4923 ADTLAGQITWAEIIALRRRAYAMLDNPVMPGPNRDRAIPWPAF
Mb2157c|M.bovis_AF2122/97 AEALAGRIAAAEIGALRRRAQSLLDQPVMPGPNGHRPIPWPAF
Rv2133c|M.tuberculosis_H37Rv AEALAGRIAAAEIGALRRRAQSLLDQPVMPGPNGHRPIPWPAF
MAV_2359|M.avium_104 GDELAEQITRAEIAALRLRAHALLDNPVMPGPNRHRPIPWPAF
Mflv_3046|M.gilvum_PYR-GCK GAELTDHITPREVAALRARVVALLRNPVMPTPDRRRPIPWPAF
Mvan_3480|M.vanbaalenii_PYR-1 GAELCGLITPREVAALRARVVGLLGNPVMPTPDRRRPIPWPAF
MSMEG_4191|M.smegmatis_MC2_155 AEQLCGHITDREIAALRARIVAMLNNPVMPTPDRHRPIPWPAF
TH_2361|M.thermoresistible__bu AEELRAHITEREVAALRSRVHALLDNPVMPTPDRRRPIPWPAF
MAB_2111|M.abscessus_ATCC_1997 GTVLEAHVTTEEVAALRQRAAMMLDEPVMPTPDRNRPIPWPAF
. * :: *: ** * :* :**** *: *.******