For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_0541 (panC)

annotation: pantoate--beta-alanine ligase
coordinates: 542296 - 543228
length: 310

MTSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGALHEGHLTLVRHARKVPGAVVV
VSIFVNPLQFGPGEDLEAYPRTLDSDVAKLREEGVELVFAPNAEAMYPHGRRTTVQPGPLGAELEGASRP
THFAGMLTVVLKLLQIVAPDRAYFGEKDYQQLVLIRQMVTDLNITTRIVPVPIVREADGLAMSSRNVYLS
EEHREQAGALSAALLAGIYSASAGVEAALDAARAVLDEVPAIEVDYLEVRGADLGPAPAHGPGRMLVAAK
LGSTRLLDNVPIEIGPTGPTDPDHELPWRN
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0541panC-100% (310)pantoate--beta-alanine ligase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3632cpanC1e-10967.77% (301) pantoate--beta-alanine ligase
M. gilvum PYR-GCKMflv_1424panC1e-12069.01% (313) pantoate--beta-alanine ligase
M. tuberculosis H37RvRv3602cpanC1e-10967.77% (301) pantoate--beta-alanine ligase
M. leprae Br4923MLBr_00230panC1e-10464.67% (300) pantoate--beta-alanine ligase
M. marinum MMMAR_5105panC1e-11469.54% (302) pantoate--beta-alanine ligase PanC
M. avium 104MAV_0551panC1e-11067.43% (304) pantoate--beta-alanine ligase
M. smegmatis MC2 155MSMEG_6097panC1e-11568.98% (303) pantoate--beta-alanine ligase
M. thermoresistible (build 8)TH_2351panC1e-11669.61% (306) PROBABLE PANTOATE--BETA-ALANINE LIGASE PANC (PANTOTHENATE
M. ulcerans Agy99MUL_4184panC1e-11469.54% (302) pantoate--beta-alanine ligase
M. vanbaalenii PYR-1Mvan_5364panC1e-11470.63% (303) pantoate--beta-alanine ligase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6097|M.smegmatis_MC2_155      MTISRTPK----FSAGELNVYSAPADVAAVTRALRTAGRRIVLVPTMGAL
TH_2351|M.thermoresistible__bu      MTVRTSPT----FTAGQLNVYTQPRAVGEVCRALRATGRRVMLVPTMGAL
Mflv_1424|M.gilvum_PYR-GCK          MGMGGAPK----FVAGQLNLYHRPTDVSAVTRALRATGRRIILVPTMGAL
Mvan_5364|M.vanbaalenii_PYR-1       MTRRDTPK----FTAGQLNVYTRPGDVAAVTRALRATGRRIVLVPTMGAL
MAB_0541|M.abscessus_ATCC_1997      MTSLYGPKGPKGYLRGELTVHHDPETMYDVSKALRHTGRRIVLVPTMGAL
Mb3632c|M.bovis_AF2122/97           MT-----I--PAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGAL
Rv3602c|M.tuberculosis_H37Rv        MT-----I--PAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGAL
MLBr_00230|M.leprae_Br4923          MTN--SRQ--PAFNPGELNVYSTPRDVTNVSSALRHTGRRVMLVPTMGAL
MAV_0551|M.avium_104                MK--------PAFTAGELNTYTSPGDVTAVSRALRHTGRRVMLVPTMGAL
MMAR_5105|M.marinum_M               MRANAGRA--PVFKPGELNIYSAPRDVGEVSRALRHTGRRVMLVPTMGAL
MUL_4184|M.ulcerans_Agy99           MRANAGRA--PVFKPGELNVYSAPRDVGEVSRALRHTGRRVMLVPTMGAL
                                    *           :  *:*. :  *  :  *  *** :***::********

MSMEG_6097|M.smegmatis_MC2_155      HEGHLTLVRAAKRTPGAVVVVSIFVNPLQFGPNEDLNAYPRTLEDDLTAL
TH_2351|M.thermoresistible__bu      HDGHLALVRAAKRVQGAVVVVSIFVNPLQFGANEDLDTYPRTLDDDLAAL
Mflv_1424|M.gilvum_PYR-GCK          HDGHLSLVRAAKRAPGAVVVVSIFVNPLQFGAGEDLDAYPRTLDEDLALL
Mvan_5364|M.vanbaalenii_PYR-1       HEGHLTLIRAAKRVTGAVVVVSIFVNPLQFAANEDLGAYPRTLDADLDAL
MAB_0541|M.abscessus_ATCC_1997      HEGHLTLVRHARKVPGAVVVVSIFVNPLQFGPGEDLEAYPRTLDSDVAKL
Mb3632c|M.bovis_AF2122/97           HEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQL
Rv3602c|M.tuberculosis_H37Rv        HEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQL
MLBr_00230|M.leprae_Br4923          HNGHLALVRAAKRVPGSVVVVSIFVNPLQFGAAEDLDTYPCTFDDDLALL
MAV_0551|M.avium_104                HDGHLALVRAAKRVPGSVVVVSIFVNPLQFSAGEDLDAYPRTLDDDLALL
MMAR_5105|M.marinum_M               HEGHLALVRAAKRTPGAVVVVSIFVNPLQFGAGEDLDAYPRTLDQDLAKL
MUL_4184|M.ulcerans_Agy99           HEGHLALVRAAKRTPGAVVVVSIFVNPLQFGAGEDLDAYPRTLDQDLAKL
                                    *:***:*:* *::. *:**********:**.. *** :** * : *:  *

MSMEG_6097|M.smegmatis_MC2_155      RAEGVEIVFTPTGSDMYPDGTRTSVHPGPLGDDLEGSSRPGHFAGVLTVV
TH_2351|M.thermoresistible__bu      REEGVEIAFTPTVDDMYPDGPRTSVQPGPLADELEGASRPGHFAGVLTVV
Mflv_1424|M.gilvum_PYR-GCK          REEGVEVVFAPTANDMYPNGMRTTVHPGPIGAELEGAVRPTHFAGMLTVV
Mvan_5364|M.vanbaalenii_PYR-1       RAEGVDIAFTPTADDMYPNGMRTTVHPGPLGAELEGALRPTHFAGVLTVV
MAB_0541|M.abscessus_ATCC_1997      REEGVELVFAPNAEAMYPHGRRTTVQPGPLGAELEGASRPTHFAGMLTVV
Mb3632c|M.bovis_AF2122/97           RAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVV
Rv3602c|M.tuberculosis_H37Rv        RAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVV
MLBr_00230|M.leprae_Br4923          RAEDVEIVFTPTAAAMYPHGLRTTVRPGALAFELEGGPRPNHFDGVLTVV
MAV_0551|M.avium_104                RSEGVEIAFTPTAAAMYPNGLRTTVQPGPLAAELEGGPRPTHFAGVLTVV
MMAR_5105|M.marinum_M               RAEGVEIAFTPTAASMYPNGLRTTVQPGPLAAELEGGSRPTHFAGVLTVV
MUL_4184|M.ulcerans_Agy99           RAEGVEIAFTPTAASMYPNGLRTTVQPGPMAAELEGGSRPTHFAGVLTVV
                                    * *.*::.*:*.   ***.* **:*:**.:. :***. ** ** *:****

MSMEG_6097|M.smegmatis_MC2_155      LKLFSIVRPDRAYFGEKDYQQLTLLRQMVADLNVDVQIVGVPTVRESDGL
TH_2351|M.thermoresistible__bu      LKLLQIVRPDSAFFGEKDYQQLVLIRQLVKDLNVDVQIVGVPTVREADGL
Mflv_1424|M.gilvum_PYR-GCK          LKLFNIIAPDRAYFGEKDYQQLALIRQMVSDLDLDIQIQGVPTVREADGL
Mvan_5364|M.vanbaalenii_PYR-1       LKLFNTVRPDRAYFGEKDFQQLALIRQMVTDLDLEVEIQGVPIVREPDGL
MAB_0541|M.abscessus_ATCC_1997      LKLLQIVAPDRAYFGEKDYQQLVLIRQMVTDLNITTRIVPVPIVREADGL
Mb3632c|M.bovis_AF2122/97           LKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGL
Rv3602c|M.tuberculosis_H37Rv        LKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGL
MLBr_00230|M.leprae_Br4923          LKLLQIVRPDRVFFGEKDYQQLVLIRQMVADLNVDVVVVGVPTVREVDGL
MAV_0551|M.avium_104                CKLLQIVRPDRIFFGEKDYQQLVMIRQMVADLNIDVQVVGVPTVREADGL
MMAR_5105|M.marinum_M               LKLLQIVAPDRAFFGEKDYQQLVLIRQMVADLNVNVQVIGVPIVREHDGL
MUL_4184|M.ulcerans_Agy99           LKLLQIVAPDRAFFGEKDYQQLVLIRQMVADLNVNVQVIGVPIVREHDGL
                                     **:. : **  :*****:***.::**:* *:::   :  ** *** ***

MSMEG_6097|M.smegmatis_MC2_155      ALSSRNRYLDKDQREQAGALSAALLAGKYAAAGGAEAALDAARAVLDEVP
TH_2351|M.thermoresistible__bu      AMSSRNRYLTDEQREQAGALSAALLAGSYAAPGGAAAALDAARAVLDEVP
Mflv_1424|M.gilvum_PYR-GCK          AMSSRNRFLAAEEREQAGALSAALLAGMYAASAGVAGALDAARAVLDEVP
Mvan_5364|M.vanbaalenii_PYR-1       AMSSRNRYLDAVQREQAGALSAALLAGMYAAGEGTAAAVDAARAVLDEVP
MAB_0541|M.abscessus_ATCC_1997      AMSSRNVYLSEEHREQAGALSAALLAGIYSASAGVEAALDAARAVLDEVP
Mb3632c|M.bovis_AF2122/97           AMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAP
Rv3602c|M.tuberculosis_H37Rv        AMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAP
MLBr_00230|M.leprae_Br4923          AMSSRNCYLDPVQRDLAAALSAALTAGAHAATGGAQAALDAARAVLDATP
MAV_0551|M.avium_104                AMSSRNRYLDATQRELAVTLSAALTAGAHAAHLGGAAALRAARAVLDAVP
MMAR_5105|M.marinum_M               AMSSRNRYLDPAQREAAIALSAALTAGAHAATAGVQAALDAARGVLEAVP
MUL_4184|M.ulcerans_Agy99           AMSSRNRYLDPAQREAAIALSAALTAGAHAATAGVQAALDAARGVLEAVP
                                    *:**** :*   .*  * :***** *. ::*  *  .*: ***.**: .*

MSMEG_6097|M.smegmatis_MC2_155      ALEVDYLQVRDPMLGPAPAEGQARLLVAARLGRTRLIDNIAIDVGASAGI
TH_2351|M.thermoresistible__bu      EIEVDYLELRDPMLGPAPPYGPGRMLVAARLGDTRLLDNIAIDIGASAGI
Mflv_1424|M.gilvum_PYR-GCK          ALQLDYLEIRDPMLGPPPAEGPGRILVAARLGRTRLIDNIAIDIGASAGI
Mvan_5364|M.vanbaalenii_PYR-1       AIEVDYLEVRDAMLGPAPEVGMGRMLVAGRLGATRLLDNIAIDIGVPSGP
MAB_0541|M.abscessus_ATCC_1997      AIEVDYLEVRGADLGPAPAHGPGRMLVAAKLGSTRLLDNVPIEIGPTGPT
Mb3632c|M.bovis_AF2122/97           GVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGT
Rv3602c|M.tuberculosis_H37Rv        GVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGT
MLBr_00230|M.leprae_Br4923          GLVVDYVELRDAGLGPMRDNTFGRLLVAARLGATRLLDNISIEIGNFSGI
MAV_0551|M.avium_104                ELTVDYLELRDAGLGPAPAHGSARLLVAARLGNTRLLDNIEMQIETPAGT
MMAR_5105|M.marinum_M               GIVVDYVELRDGELGPVSPSGSGRLLVAVRFGTTRLLDNVAIEIESIAGT
MUL_4184|M.ulcerans_Agy99           GIVVDYVELRDGELGPVSPSGSGRLLVAVRFGTTRLLDNVAIEIESIAGT
                                     : :**:::*.  ***      .*:*** ::* ***:**: :::   .  

MSMEG_6097|M.smegmatis_MC2_155      DGHPRVGNDQNHELPWRN
TH_2351|M.thermoresistible__bu      DGHPLVAADRGSELPWRN
Mflv_1424|M.gilvum_PYR-GCK          DGHPRTAHGKSSEIPWRN
Mvan_5364|M.vanbaalenii_PYR-1       G---RQAEFDEHELPWRN
MAB_0541|M.abscessus_ATCC_1997      D--------PDHELPWRN
Mb3632c|M.bovis_AF2122/97           DR-PDGYR-AILESHWRN
Rv3602c|M.tuberculosis_H37Rv        DR-PDGYR-AILESHWRN
MLBr_00230|M.leprae_Br4923          AS-PDECRVEHAQTPWMK
MAV_0551|M.avium_104                AG-PDGDR-QYAQSPWRN
MMAR_5105|M.marinum_M               DG-QPVGPDGRVQSPWRN
MUL_4184|M.ulcerans_Agy99           DG-QPVGPDGRVQSPWRN
                                                :  * :