# command: ../../../transit/src/transit.py pathway_enrichment resampling_glyc_chol.txt /pacific/home/ioerger/transit/src/pytransit/analysis/H37Rv_COG_roles.dat /pacific/home/ioerger/transit/src/pytransit/analysis/COG_roles.dat pathways_glyc_chol_COG.txt # date: 2020-02-29 09:30:06.905401 # method=FISHER, PC=2 # genes with associations=2871 out of 3990 total # significant genes (qval<0.05): 75 # 19 out of 25 pathways have >=1 gene; max has 521 #pathway total_genes(M) genes_in_path(n) significant_genes(N) signif_genes_in_path(k) expected k+PC n_adj_by_PC enrichement pval qval description genes Q 3990 197 75 15 3.7 17 303 2.982 7.571273996993297e-06 0.00014385420594287265 Secondary metabolites biosynthesis, transport and catabolism Rv1193/fadD36 Rv1432/- Rv2048c/pks12 Rv3494c/mce4F Rv3495c/lprN Rv3496c/mce4D Rv3497c/mce4C Rv3498c/mce4B Rv3499c/mce4A Rv3500c/yrbE4B Rv3501c/yrbE4A Rv3535c/- Rv3545c/cyp125 Rv3561/fadD3 Rv3825c/pks2 I 3990 189 75 13 3.55 15 295 2.703 8.277467327002055e-05 0.0007863593960651952 Lipid transport and metabolism Rv0244c/fadE5 Rv1428c/- Rv1627c/- Rv3540c/ltp2 Rv3543c/fadE29 Rv3544c/fadE28 Rv3546/fadA5 Rv3551/- Rv3556c/fadA6 Rv3560c/fadE30 Rv3563/fadE32 Rv3564/fadE33 Rv3570c/- R 3990 521 75 14 9.79 16 627 1.357 0.07023010427301078 0.3831839178397165 General function prediction only Rv0450c/mmpL4 Rv0693/pqqE Rv0805/- Rv1129c/- Rv1130/- Rv1183/mmpL10 Rv2942/mmpL7 Rv3502c/fabG Rv3526/- Rv3542c/- Rv3549c/- Rv3553/- Rv3559c/- Rv3569c/bphD P 3990 135 75 5 2.54 7 241 1.542 0.08067029849257189 0.3831839178397165 Inorganic ion transport and metabolism Rv0362/mgtE Rv0390/- Rv1283c/oppB Rv2684/arsA Rv3200c/- C 3990 222 75 6 4.17 8 328 1.297 0.15956386499457234 0.5228238409682431 Energy production and conversion Rv0694/lldD1 Rv0761c/adhB Rv1131/gltA1 Rv3537/- Rv3571/hmp Rv3696c/glpK V 3990 49 75 2 0.92 4 155 1.37 0.16510226556891885 0.5228238409682431 Defense mechanisms Rv2936/drrA Rv2938/drrC K 3990 201 75 5 3.78 7 307 1.211 0.21674193258432803 0.588299531300319 Transcription Rv1129c/- Rv1963c/mce3R Rv2506/- Rv3484/cpsA Rv3575c/- O 3990 88 75 2 1.65 4 194 1.096 0.29998249196309273 0.7124584184123453 Posttranslational modification, protein turnover, chaperones Rv2462c/tig Rv3421c/- E 3990 182 75 3 3.42 5 288 0.923 0.45943322833132577 0.8562888143841759 Amino acid transport and metabolism Rv0391/metZ Rv2569c/- Rv3568c/bphC U 3990 27 75 0 0.51 2 133 0.797 0.4595126384307819 0.8562888143841759 Intracellular trafficking, secretion, and vesicular transport D 3990 44 75 0 0.83 2 150 0.707 0.5407137623579726 0.8562888143841759 Cell cycle control, cell division, chromosome partitioning T 3990 99 75 1 1.86 3 205 0.777 0.5435169102008456 0.8562888143841759 Signal transduction mechanisms Rv1626/- G 3990 120 75 1 2.26 3 226 0.704 0.6222277049747147 0.8562888143841759 Carbohydrate transport and metabolism Rv0485/- F 3990 65 75 0 1.22 2 171 0.621 0.6309496527041296 0.8562888143841759 Nucleotide transport and metabolism M 3990 114 75 0 2.14 2 220 0.483 0.7920205612018485 0.9722196692261906 Cell wall/membrane/envelope biogenesis H 3990 141 75 0 2.65 2 247 0.43 0.8530500116081483 0.9722196692261906 Coenzyme transport and metabolism J 3990 160 75 0 3.01 2 266 0.399 0.8862120072954369 0.9722196692261906 Translation, ribosomal structure and biogenesis L 3990 218 75 0 4.1 2 324 0.328 0.9504107894001739 0.9722196692261906 Replication, recombination and repair S 3990 256 75 0 4.81 2 362 0.294 0.9722196692261906 0.9722196692261906 Function unknown